SCHEMBL8927014

SCHEMBL8927014

CCN(CC)c1ccc(/C=C/c2ccc([N+](=O)[O-])cc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.69
MAPT P10636 6/20 0.69
MEN1 O00255 5/20 0.69
KMT2A Q03164 5/20 0.69
LMNA P02545 1/20 0.69
PTGS2 P35354 7/20 0.58
ALDH3A1 P30838 1/20 0.55
ALDH1A3 P47895 1/20 0.55
TLR9 Q9NR96 2/20 0.54
APP P05067 1/20 0.53
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53
FBP1 P09467 1/20 0.51
PTGS1 P23219 2/20 0.50
CYP19A1 P11511 2/20 0.50
CRHBP P24387 1/20 0.47
ATM Q13315 1/20 0.47
CRHR2 Q13324 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8927017 1.00 ALDH1A1 (0.69) ALDH1A1MAPTMEN1KMT2ALMNA
SCHEMBL160430 0.89 ALDH1A1 (0.57) ALDH1A1MAPTMEN1KMT2ALMNA
SCHEMBL15870255 0.88 ALDH1A1 (0.55) ALDH1A1MAPTMEN1KMT2ALMNA
SCHEMBL9847275 0.88 MAPT (0.58) ALDH1A1MAPTMEN1KMT2ALMNA
SCHEMBL531065 0.88 ALDH1A1 (0.55) ALDH1A1MAPTMEN1KMT2ALMNA
SCHEMBL531064 0.88 ALDH1A1 (0.55) ALDH1A1MAPTMEN1KMT2ALMNA
SCHEMBL9362623 0.87 PTGS2 (0.55) ALDH1A1MAPTMEN1KMT2ALMNA
SCHEMBL9362626 0.87 PTGS2 (0.55) ALDH1A1MAPTMEN1KMT2ALMNA
SCHEMBL9847256 0.87 MAPT (0.54) ALDH1A1MAPTMEN1KMT2ALMNA
SCHEMBL9847298 0.85 MAPT (0.58) ALDH1A1MAPTMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-60159832-A None JP disclosed
US-9575246-B2 Prepolymer, curable material, coating composition, non-linear optical material, optical waveguide and light control device ASAHI GLASS COMPANY, LIMITED (JP) 2017-02-21 US disclosed
EP-2889684-A1 PREPOLYMER, CURABLE MATERIAL, COATING COMPOSITION, NON-LINEAR OPTICAL MATERIAL, OPTICAL WAVEGUIDE AND LIGHT CONTROL DEVICE Asahi Glass Company, Limited (JP) 2015-07-01 EP disclosed
US-20150153509-A1 PREPOLYMER, CURABLE MATERIAL, COATING COMPOSITION, NON-LINEAR OPTICAL MATERIAL, OPTICAL WAVEGUIDE AND LIGHT CONTROL DEVICE ASAHI GLASS COMPANY, LIMITED (JP) 2015-06-04 US disclosed
US-5656204-A Optical element and process for producing the same FUJI XEROX CO., LTD. (JP) 1997-08-12 US disclosed
EP-0473496-B1 Process of manufacturing a monomodal optical waveguide in electro-optical polymer, as well as such an optical wave guide FRANCE TELECOM (FR) 1995-07-05 EP disclosed
EP-0418654-B1 Coupler-type optical switch and process for producing the same SUMITOMO ELECTRIC INDUSTRIES (JP) 1994-12-21 EP disclosed
EP-0326133-B1 Organic nonlinear optical material and nonlinear optical device NIPPON TELEGRAPH & TELEPHONE (JP) 1994-12-07 EP disclosed
US-5182783-A PROCESS FOR MANUFACTURING A MONOMODE OPTICAL WAVEGUIDE MADE OF A POLYMER AND ENDOWED WITH ELECTROOPTIC PROPERTIES, AND SUCH AN OPTICAL WAVEGUIDE FRANCE TELECOM (FR) 1993-01-26 US disclosed
EP-0313475-B1 AN OPTICAL ARTICLE CONTAINING A TRANSMISSION MEDIUM EXHIBITING A HIGH LEVEL OF SECOND ORDER POLARIZATION SUSCEPTIBILITY EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1992-12-23 EP disclosed
US-5108200-A Medium surrounding photocoupler contains optic material who refrative index changes by action of electric or magnetic field SUMITOMO ELECTRIC INDUSTRIES LTD. (JP) 1992-04-28 US disclosed
EP-0473496-A1 Process of manufacturing a monomodal optical waveguide in electro-optical polymer, as well as such an optical wave guide FRANCE TELECOM (FR) 1992-03-04 EP disclosed
EP-0418654-A1 Coupler-type optical switch and process for producing the same SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 1991-03-27 EP disclosed
US-4999139-A Aminonitrostyrene Compound; Including a Polarizer, an Optical Resonator an a Reflector NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1991-03-12 US disclosed
US-4997595-A Organic nonlinear optical material and nonlinear optical device NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1991-03-05 US disclosed
EP-0406888-A2 Nonlinear optical polymer composition and method for producing the same SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 1991-01-09 EP disclosed
US-4886339-A MOLECULAR DIPOLES HELD IN POLAR ALIGNMENT BY A CROSSLINKED POLYMERIC BINDER; STABILITY EASTMAN KODAK COMPANY (US) 1989-12-12 US disclosed
EP-0326133-A2 Organic nonlinear optical material and nonlinear optical device NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1989-08-02 EP disclosed
EP-0313475-A2 An optical article containing a transmission medium exhibiting a high level of second order polarization susceptibility EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1989-04-26 EP disclosed
JP-S60159832-A OPTICAL BISTABLE ELEMENT MITSUBISHI CHEM IND LTD 1985-08-21 JP disclosed