Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL687758 | 0.81 | CYP19A1 (0.32) | CYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL29565043 | 0.81 | CYP19A1 (0.32) | CYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL31498264 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL630668 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL7926584 | 0.78 | CYP19A1 (0.30) | CYP11B1CYP11B2CYP19A1 | |
| Ethylene SCHEMBL5512109 | 0.78 | CYP19A1 (0.30) | CYP11B1CYP11B2CYP19A1 | |
| Fluoride Ion SCHEMBL1131352 | 0.77 | — | — | |
| Bromide SCHEMBL2526728 | 0.77 | HTR2A (0.32) | — | |
| Toluene SCHEMBL7806717 | 0.76 | LMNA (0.41) | — | |
| Methylsulfanylmethane SCHEMBL1044394 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696045-A | USING MIXTURE OF ZIRCONOCENE CATALYSTS | TARGOR GMBH (DE) | 1997-12-09 | — | — | US | disclosed |