SCHEMBL8927342

SCHEMBL8927342

CCCCNC(=O)NS(=O)(=O)c1cccc(C)c1S(=O)(=O)CCC

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 7/20 0.55
CYP2C9 P11712 2/20 0.53
ALDH1A1 P00352 1/20 0.53
LMNA P02545 1/20 0.53
ALB P02768 1/20 0.53
TSHR P16473 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
TBXA2R P21731 9/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16758296 0.83 CYP2C9 (0.62) FBP1CYP2C9ALDH1A1LMNAALB
SCHEMBL6536403 0.74 FBP1 (0.50) FBP1CYP2C9ALDH1A1LMNAALB
SCHEMBL11082692 0.74 FBP1 (0.52) FBP1CYP2C9ALDH1A1LMNAALB
SCHEMBL10642741 0.74 CYP2C9 (0.56) FBP1CYP2C9ALDH1A1LMNAALB
SCHEMBL8448505 0.73 CYP2C9 (0.54) FBP1CYP2C9ALDH1A1LMNAALB
SCHEMBL10569228 0.73 CYP2C9 (0.54) FBP1CYP2C9ALDH1A1LMNAALB
SCHEMBL6464360 0.73 PTGER1 (0.59) FBP1CYP2C9ALDH1A1LMNAALB
SCHEMBL10759550 0.72 CYP2C9 (0.57) FBP1CYP2C9ALDH1A1LMNAALB
SCHEMBL8927096 0.72 CYP2C9 (0.53) FBP1CYP2C9ALDH1A1LMNAALB
SCHEMBL11119863 0.72 HTT (0.58) FBP1CYP2C9ALDH1A1LMNAALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5608143-A NUCLEIC ACID PROMOTER FRAGMENT E. I. DU PONT DE NEMOURS AND COMPANY (US) 1997-03-04 US disclosed
US-5364780-A Genetic engineering with DNA and promoters E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-11-15 US disclosed
EP-0463056-A1 EXTERNAL REGULATION OF GENE EXPRESSION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-01-02 EP disclosed
WO-1990011361-A1 EXTERNAL REGULATION OF GENE EXPRESSION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-10-04 WO disclosed
EP-0388186-A1 External regulation of gene expression E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-09-19 EP disclosed