SCHEMBL6464360

SCHEMBL6464360

CCCCNC(=O)NS(=O)(=O)c1ccccc1-c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PTGER1 P34995 1/20 0.59
PTGER3 P43115 1/20 0.59
AGTR2 P50052 3/20 0.57
AGTR1 P30556 2/20 0.57
CYP2C9 P11712 2/20 0.54
ALDH1A1 P00352 1/20 0.54
LMNA P02545 1/20 0.54
ALB P02768 1/20 0.54
TSHR P16473 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
FBP1 P09467 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8686960 0.92 AGTR2 (0.56) PTGER1PTGER3AGTR2AGTR1ALDH1A1
SCHEMBL16758296 0.82 CYP2C9 (0.62) CYP2C9ALDH1A1LMNAALBTSHR
SCHEMBL10733371 0.82 FBP1 (0.51) PTGER1PTGER3AGTR2AGTR1CYP2C9
SCHEMBL6464356 0.81 CYP2C9 (0.72) CYP2C9ALDH1A1LMNAALBTSHR
SCHEMBL3632239 0.80 CA12 (0.62) ALDH1A1LMNATSHRTDP1
SCHEMBL184964 0.80 CYP2C9 (0.76) CYP2C9ALDH1A1LMNAALBTSHR
SCHEMBL8997324 0.80 SOAT1 (0.58) AGTR2AGTR1
SCHEMBL10642741 0.80 CYP2C9 (0.56) PTGER1PTGER3CYP2C9ALDH1A1LMNA
SCHEMBL10547925 0.80 FBP1 (0.49) PTGER1PTGER3AGTR2AGTR1CYP2C9
Methyl Alcohol SCHEMBL28260710 0.79 CYP2C9 (0.74) CYP2C9ALDH1A1LMNAALBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5449657-A Sulfonyl (thio)ureas NEW OJI PAPER CO., LTD. (JP) 1995-09-12 US claimed
EP-0615859-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-09-21 EP claimed
US-20050106491-A1 Heat sensitive recording material CIBA SPECIALTY CHEMICALS CORP. 2005-05-19 US disclosed
US-6740465-B2 MULTILAYER; TRANSPARENT SUPPORT; HEAT SENSITIVE ELEMENT AND RELEASE AGENT SIPIX IMAGING, INC. 2004-05-25 US disclosed
EP-1289768-A2 IMAGING MEDIA CONTAINING HEAT DEVELOPABLE PHOTOSENSITIVE MICROCAPSULES Sipix Imaging, Inc. (US) 2003-03-12 EP disclosed
US-20020155372-A1 Imaging media containing heat developable photosensitive microcapsules SIPIX IMAGING, INC. 2002-10-24 US disclosed
WO-2001092024-A2 IMAGING MEDIA CONTAINING HEAT DEVELOPABLE PHOTOSENSITIVE MICROCAPSULES SIPIX IMAGING, INC. (US) 2001-12-06 WO disclosed
US-5449657-A Sulfonyl (thio)ureas NEW OJI PAPER CO., LTD. (JP) 1995-09-12 US disclosed
EP-0615859-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-09-21 EP disclosed