Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 18/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8927498 | 0.83 | F2 (0.42) | F2 | |
| SCHEMBL8927494 | 0.82 | F2 (0.45) | F2 | |
| SCHEMBL8716988 | 0.81 | F2 (0.58) | F2 | |
| SCHEMBL8926247 | 0.80 | CPN1 (0.37) | F2 | |
| SCHEMBL8926218 | 0.70 | F2 (0.42) | F2SLC1A2 | |
| SCHEMBL8947691 | 0.69 | F2 (0.55) | F2 | |
| SCHEMBL8927436 | 0.67 | F2 (0.41) | F2 | |
| SCHEMBL8717139 | 0.67 | F2 (0.46) | F2 | |
| SCHEMBL8719964 | 0.66 | F2 (0.59) | F2 | |
| SCHEMBL8926802 | 0.66 | F2 (0.52) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677448-A | CHEMICAL INTERMEDIATES FOR MAKING ANTAGONIST OF THROMBIN, TREATING THROMBOSIS, STROKE, INFLAMMATION, ARTERIOSCLEROSIS, CARDIOVASCULAR DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1997-10-14 | — | — | US | disclosed |