Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 4/20 | 0.36 |
| ▸ | PLG | P00747 | 3/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.36 |
| ▸ | F2 | P00734 | 16/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.34 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.34 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | CTRC | Q99895 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8927494 | 0.83 | F2 (0.45) | F10F2MMP1MMP2MMP3 | |
| SCHEMBL8927498 | 0.83 | F2 (0.42) | F10PLGF2 | |
| SCHEMBL8927392 | 0.80 | F2 (0.42) | F2 | |
| SCHEMBL8719867 | 0.77 | F2 (0.51) | F2 | |
| SCHEMBL8926218 | 0.68 | F2 (0.42) | F10PLGF2 | |
| SCHEMBL18265351 | 0.63 | EED (0.49) | CPN1CPB2F10F2TPSAB1 | |
| SCHEMBL15373361 | 0.62 | EED (0.46) | CPN1CPB2F2TPSAB1TPSD1 | |
| SCHEMBL1542957 | 0.61 | F2 (0.48) | CPN1CPB2F2TPSAB1TPSD1 | |
| SCHEMBL14633701 | 0.61 | TPSAB1 (0.38) | CPN1CPB2F10PRSS1F2 | |
| SCHEMBL14599993 | 0.61 | TPSAB1 (0.38) | CPN1CPB2F10PRSS1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677448-A | CHEMICAL INTERMEDIATES FOR MAKING ANTAGONIST OF THROMBIN, TREATING THROMBOSIS, STROKE, INFLAMMATION, ARTERIOSCLEROSIS, CARDIOVASCULAR DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1997-10-14 | — | — | US | disclosed |