Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 16/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8926247 | 0.83 | CPN1 (0.37) | F2F10MMP1MMP2MMP3 | |
| SCHEMBL8927498 | 0.82 | F2 (0.42) | F2F10 | |
| SCHEMBL8927392 | 0.82 | F2 (0.42) | F2 | |
| SCHEMBL8717237 | 0.82 | F2 (0.61) | F2 | |
| SCHEMBL7297918 | 0.72 | F2 (0.56) | F2 | |
| SCHEMBL8919776 | 0.72 | F2 (0.56) | F2 | |
| Hydrochloric Acid SCHEMBL8919868 | 0.71 | F2 (0.81) | F2 | |
| Hydrochloric Acid SCHEMBL7289522 | 0.71 | F2 (0.81) | F2 | |
| SCHEMBL8926218 | 0.69 | F2 (0.42) | F2F10 | |
| SCHEMBL8926802 | 0.68 | F2 (0.52) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677448-A | CHEMICAL INTERMEDIATES FOR MAKING ANTAGONIST OF THROMBIN, TREATING THROMBOSIS, STROKE, INFLAMMATION, ARTERIOSCLEROSIS, CARDIOVASCULAR DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1997-10-14 | — | — | US | disclosed |