⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2248729 | 0.78 | — | — | |
| SCHEMBL5888231 | 0.75 | — | — | |
| SCHEMBL9485283 | 0.68 | — | — | |
| SCHEMBL28189661 | 0.67 | — | — | |
| SCHEMBL1239517 | 0.67 | HTR3E (0.30) | — | |
| SCHEMBL9485285 | 0.64 | — | — | |
| SCHEMBL11762049 | 0.64 | — | — | |
| SCHEMBL27277985 | 0.61 | ADRB1 (0.31) | — | |
| SCHEMBL29079106 | 0.61 | — | — | |
| SCHEMBL2356063 | 0.60 | HIF1A (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118745132-A | Cedrus alcohol derivative and preparation method and application thereof | 沈阳药科大学 | 2024-10-08 | — | — | CN | disclosed |
| CN-1221536-C | New derivatives of cyano-aryl (or cyanoheteroaryl)-carbonyl-piperazinyl- pyrimidines, their preparation and application as medication | ESTEVE LABOR DR (ES) | 2005-10-05 | — | — | CN | disclosed |
| CN-1469866-A | New derivatives of cyano-aryl (or cyanoheteroaryl)-carbonyl-piperazinyl- pyrimidines, their preparation and application as medication | ��˹���IJ�ʿʵ���ҹɷ�����˾ | 2004-01-21 | — | — | CN | disclosed |
| US-5629002-A | THIOCYANATES IN SYNERGISTIC COMBINATION WITH ESTROGENS, SULFUR, SULFIDES, VASODILATORS, PROTEIN HYDROLYZATES, AMINO ACIDS, CARBOXYLIC ACIDS, VITAMINS | WEUFFEN WOLFGANG (DE) | 1997-05-13 | — | — | US | disclosed |
| US-5373012-A | Useful in treatment of hair growth and cardiovascular disorder | THE UPJOHN COMPANY (US) | 1994-12-13 | — | — | US | disclosed |
| EP-0557301-A1 | 5-FLUORO-2,4,6-PYRIMIDINETRIAMINE COMPOUNDS. | UPJOHN CO (US) | 1993-09-01 | — | — | EP | disclosed |
| WO-1992015290-A1 | METHODS FOR TREATMENT OF SCARRING FIBROTIC ALOPECIA | KLIGMAN ALBERT M (US) | 1992-09-17 | — | — | WO | disclosed |
| WO-1992012699-A1 | COSMETIC OR PHARMACEUTICAL COMPOSITIONS FOR IMPROVING HAIR QUALITY AND PROMOTING HAIR GROWTH | WEUFFEN WOLFGANG (DE) | 1992-08-06 | — | — | WO | disclosed |
| WO-1992008705-A1 | 5-FLUORO-2,4,6-PYRIMIDINETRIAMINE COMPOUNDS | THE UPJOHN COMPANY (US) | 1992-05-29 | — | — | WO | disclosed |
| US-4916133-A | Stimulating hair growth | L'OREAL (FR) | 1990-04-10 | — | — | US | disclosed |
| US-4916133-A | Stimulating hair growth | L'OREAL (FR) | 1990-04-10 | — | — | US | disclosed |
| US-4916133-A | Stimulating hair growth | L'OREAL (FR) | 1990-04-10 | — | — | US | disclosed |
| US-4885296-A | FOR INDUCING AND STIMULATING HAIR GROWTH | L'OREAL (FR) | 1989-12-05 | — | — | US | disclosed |
| US-4885296-A | FOR INDUCING AND STIMULATING HAIR GROWTH | L'OREAL (FR) | 1989-12-05 | — | — | US | disclosed |
| US-4885296-A | FOR INDUCING AND STIMULATING HAIR GROWTH | L'OREAL (FR) | 1989-12-05 | — | — | US | disclosed |