Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.54 |
| ▸ | BCHE | P06276 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10815679 | 0.87 | ACHE (0.61) | ACHEBCHEALDH1A1NPC1RAB9A | |
| SCHEMBL10971933 | 0.80 | CYP3A4 (0.65) | ACHEBCHEALDH1A1NPC1RAB9A | |
| Metolcarb SCHEMBL118244 | 0.80 | LMNA (0.65) | ACHEBCHEALDH1A1NPC1RAB9A | |
| Metolcarb SCHEMBL29413999 | 0.80 | LMNA (0.65) | ACHEBCHEALDH1A1NPC1RAB9A | |
| SCHEMBL20264521 | 0.80 | BCHE (0.55) | ACHEBCHEALDH1A1NPC1RAB9A | |
| SCHEMBL8926556 | 0.80 | MEN1 (0.42) | ACHEALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL1747775 | 0.79 | LMNA (0.63) | ACHEALDH1A1NPC1RAB9AKDM4E | |
| Metolcarb SCHEMBL11000289 | 0.79 | LMNA (0.62) | ACHEBCHEALDH1A1NPC1RAB9A | |
| SCHEMBL4266372 | 0.79 | ACHE (0.54) | ACHEBCHEALDH1A1NPC1RAB9A | |
| Metolcarb SCHEMBL11681132 | 0.79 | LMNA (0.62) | ACHEBCHEALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614498-A | OLIGOPEPTIDES, BRONCHDILATORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-03-25 | — | — | US | disclosed |
| US-5496928-A | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0555537-A2 | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-18 | — | — | EP | disclosed |