Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | PNPLA2 | Q96AD5 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19019393 | 0.87 | TP53 (0.69) | TP53PNPLA2HDAC6APEX1TSHR | |
| SCHEMBL20057568 | 0.80 | TP53 (0.61) | TP53PNPLA2HDAC6APEX1TSHR | |
| SCHEMBL11164480 | 0.80 | TP53 (0.61) | TP53PNPLA2HDAC6APEX1TSHR | |
| SCHEMBL10425058 | 0.80 | ALDH1A1 (0.65) | TP53PNPLA2HDAC6APEX1TSHR | |
| SCHEMBL8153658 | 0.80 | HSD17B10 (0.65) | TP53PNPLA2HDAC6APEX1 | |
| SCHEMBL839236 | 0.79 | ALDH1A1 (0.63) | TP53 | |
| SCHEMBL3478037 | 0.79 | CA12 (0.44) | TP53HDAC6 | |
| SCHEMBL23169533 | 0.79 | TP53 (0.64) | TP53PNPLA2HDAC6APEX1TSHR | |
| SCHEMBL2461958 | 0.79 | MEN1 (0.65) | TP53PNPLA2HDAC6APEX1TSHR | |
| SCHEMBL20313975 | 0.79 | HDAC6 (0.69) | TP53PNPLA2HDAC6APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614498-A | OLIGOPEPTIDES, BRONCHDILATORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-03-25 | — | — | US | disclosed |
| US-5496928-A | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0555537-A2 | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-18 | — | — | EP | disclosed |