Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27291385 | 0.89 | ALDH1A1 (0.77) | ALDH1A1POLBCACNA1GHDAC8HDAC3 | |
| SCHEMBL1534196 | 0.87 | TP53 (0.64) | ALDH1A1POLBTP53HDAC8KMT2A | |
| SCHEMBL1796314 | 0.84 | POLB (0.93) | ALDH1A1POLBCACNA1GHDAC8HDAC3 | |
| SCHEMBL4654699 | 0.84 | MEN1 (0.63) | POLBHDAC8HDAC3HDAC4HDAC1 | |
| SCHEMBL29111436 | 0.84 | HDAC1 (0.56) | ALDH1A1POLBHDAC8HDAC3HDAC4 | |
| SCHEMBL9162353 | 0.83 | POLB (0.64) | ALDH1A1POLBTP53CACNA1GHDAC8 | |
| SCHEMBL1797542 | 0.83 | L3MBTL1 (0.67) | ALDH1A1POLBTP53HDAC8HDAC3 | |
| SCHEMBL15874435 | 0.83 | L3MBTL1 (0.51) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8171574 | 0.83 | ALDH1A1 (0.68) | ALDH1A1POLBTP53CACNA1GHDAC8 | |
| SCHEMBL11249589 | 0.83 | GAA (0.60) | ALDH1A1TP53HDAC8HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5631403-A | HYDROLYSIS OF HALOCARBOXANILIDE IN SOLVENT | HOECHST AG (DE) | 1997-05-20 | — | — | US | disclosed |