SCHEMBL8927699

SCHEMBL8927699

CC(S)C(=O)O.c1cc2cc(c1)C2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 3/20 0.37
PTGS2 P35354 3/20 0.37
MAPT P10636 2/20 0.37
CXCR1 P25024 2/20 0.37
CXCR2 P25025 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
KDM4E B2RXH2 2/20 0.37
LMNA P02545 2/20 0.37
HIF1A Q16665 2/20 0.37
RECQL P46063 1/20 0.37
ALDH1A1 P00352 1/20 0.37
CYP3A4 P08684 1/20 0.37
HPGD P15428 1/20 0.37
MAPK1 P28482 1/20 0.37
PMP22 Q01453 1/20 0.37
SLC22A6 Q4U2R8 1/20 0.37
HSD17B10 Q99714 1/20 0.37
CXCL8 P10145 1/20 0.37
THPO P40225 1/20 0.37
ACE P12821 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28471593 0.80 SMN1; SMN2 (0.33) PTGS1PTGS2MAPTCXCR1CXCR2
Bicarbonate SCHEMBL8044579 0.79 TDP1 (0.40) KDM4EALDH1A1HPGDHSD17B10
SCHEMBL8927749 0.78 KMO (0.47) PTGS2ACEMMECPA1ACE2
SCHEMBL26603631 0.76 KMT2A (0.34) PTGS2ACEMMECPA1ACE2
SCHEMBL29012651 0.76 RXFP1 (0.32) PTGS1PTGS2MAPTCXCR1CXCR2
Acetamide SCHEMBL11835556 0.73 PARP1 (0.40) MAPTKDM4ELMNAHIF1AALDH1A1
Malic Acid SCHEMBL27735851 0.72 SMN1; SMN2 (0.52) SMN1; SMN2CPA1
Toluene SCHEMBL18837396 0.71 LMNA (0.52) PTGS2MAPTSMN1; SMN2LMNAALDH1A1
Phenol SCHEMBL28141127 0.71 CA12 (0.52) PTGS2KDM4ELMNAHIF1AMAPK1
SCHEMBL12149426 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5614571-A Stabilizer blend containing phosphite GENERAL ELECTRIC COMPANY (US) 1997-03-25 US disclosed
US-4342875-A STABILIZERS FOR OLEFIN POLYMERS CINCINNATI-MILACRON, INC. (US) 1982-08-03 US disclosed
US-4179432-A 2-HYDROXYBENZOPHENONE, ORGANOTIN MERCAPTIDE PHOTOSTABILITY CINCINNATI MILACRON CHEMICALS, INC. (US) 1979-12-18 US disclosed
US-RE29523-E Olefinic polymers stabilized with thioacyl trivalent phosphorus compounds BORG-WARNER CORPORATION (US) 1978-01-24 US disclosed
US-4064100-A HEAT AND LIGHT STABILIZERS FOR POLYMERS, CONTAINERS FOR FOOD WESTON CHEMICAL CO., INC. (US) 1977-12-20 US disclosed
US-4012399-A ULTRAVIOLET LIGHT ABSORBERS AND STABILIZERS CINCINNATI MILACRON CHEMICALS, INC. (US) 1977-03-15 US disclosed
US-4000101-A POLYPROPYLENE WESTON CHEMICAL CORPORATION (US) 1976-12-28 US disclosed
US-3959220-A Polymer additives comprising transition metal complexes with trivalent phosphorous compounds CINCINNATI MILACRON CHEMICALS, INC. (US) 1976-05-25 US disclosed