Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CASP1 | P29466 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29588249 | 0.79 | RECQL (0.55) | ALDH1A1CASP1CASP7TSHRMAPK1 | |
| SCHEMBL11592777 | 0.79 | RECQL (0.55) | ALDH1A1CASP1CASP7TSHRMAPK1 | |
| SCHEMBL4395076 | 0.76 | CA1 (0.65) | GSTP1ALDH1A1CASP1TP53HPGD | |
| Water SCHEMBL6363255 | 0.74 | CA1 (0.62) | GSTP1ALDH1A1CASP1TP53HPGD | |
| SCHEMBL14575653 | 0.73 | CA1 (0.60) | GSTP1ALDH1A1CASP1TSHRMAPK1 | |
| SCHEMBL29364188 | 0.71 | MEN1 (0.56) | GSTP1ALDH1A1CASP1TP53HPGD | |
| SCHEMBL30130196 | 0.71 | MEN1 (0.56) | GSTP1ALDH1A1CASP1TP53HPGD | |
| SCHEMBL354514 | 0.71 | MEN1 (0.56) | GSTP1ALDH1A1CASP1TP53HPGD | |
| SCHEMBL29540906 | 0.70 | GSK3B (0.62) | GSTP1ALDH1A1CASP1TP53HPGD | |
| SCHEMBL29783117 | 0.70 | GSK3B (0.62) | GSTP1ALDH1A1CASP1TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7367993-B2 | Dyeing compositions comprising at least one 1,3-indandione derivative | L'OREAL S.A. (FR) | 2008-05-06 | — | — | US | disclosed |
| US-7367993-B2 | Dyeing compositions comprising at least one 1,3-indandione derivative | L'OREAL S.A. (FR) | 2008-05-06 | — | — | US | disclosed |
| US-5591848-A | Spiroconjugated charge-transfer dyes for optical applications | THE PENN STATE RESEARCH FOUNDATION (US) | 1997-01-07 | — | — | US | disclosed |