SCHEMBL29588249

SCHEMBL29588249

O=C1c2ccccc2C(=O)C1(Br)Br

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 3/20 0.55
ALDH1A1 P00352 3/20 0.55
MAPK1 P28482 2/20 0.55
EHMT2 Q96KQ7 2/20 0.55
ALOX12 P18054 2/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
TSHR P16473 1/20 0.55
CASP1 P29466 1/20 0.55
CA7 P43166 1/20 0.55
BACE1 P56817 1/20 0.55
CA9 Q16790 1/20 0.55
S100A4 P26447 2/20 0.50
CYP2D6 P10635 1/20 0.47
GSK3B P49841 1/20 0.46
KMT2A Q03164 3/20 0.45
CDC25B P30305 3/20 0.45
MEN1 O00255 2/20 0.45
MAPT P10636 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11592777 1.00 RECQL (0.55) RECQLALDH1A1MAPK1EHMT2ALOX12
SCHEMBL8927867 0.79 GSTP1 (0.40) RECQLALDH1A1MAPK1EHMT2ALOX12
SCHEMBL11593604 0.77 S100A4 (0.70) RECQLALDH1A1MAPK1EHMT2ALOX12
SCHEMBL9575837 0.75 RECQL (0.60) RECQLALDH1A1MAPK1EHMT2ALOX12
SCHEMBL11594662 0.74 CA1 (0.63) RECQLALDH1A1MAPK1EHMT2ALOX12
SCHEMBL14939057 0.74 ALDH1A1 (0.52) RECQLALDH1A1MAPK1EHMT2ALOX12
SCHEMBL11842335 0.72 CYP2D6 (0.53) RECQLALDH1A1MAPK1EHMT2ALOX12
SCHEMBL11136806 0.71 ALDH1A1 (0.70) RECQLALDH1A1MAPK1EHMT2ALOX12
SCHEMBL14703200 0.71 ALDH1A1 (0.55) RECQLALDH1A1MAPK1EHMT2ALOX12
SCHEMBL3658029 0.71 CA1 (1.00) RECQLALDH1A1MAPK1EHMT2ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12084583-B2 Dielectric ink composition ALPHA ASSEMBLY SOLUTIONS INC. (US) 2024-09-10 US disclosed
US-20220064466-A1 DIELECTRIC INK COMPOSITION ALPHA ASSEMBLY SOLUTIONS INC. (US) 2022-03-03 US disclosed