SCHEMBL8928059

SCHEMBL8928059

NC(=O)C=CC(C=CC(N)=O)C=CC(N)=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.37
TSHR P16473 1/20 0.37
FGFR4 P22455 1/20 0.37
GABRP O00591 2/20 0.32
GABRD O14764 2/20 0.32
GABRA1 P14867 2/20 0.32
GABRB1 P18505 2/20 0.32
GABRG2 P18507 2/20 0.32
GABRB3 P28472 2/20 0.32
GABRA5 P31644 2/20 0.32
GABRA3 P34903 2/20 0.32
GABRA2 P47869 2/20 0.32
GABRB2 P47870 2/20 0.32
GABRA4 P48169 2/20 0.32
GABRE P78334 2/20 0.32
GABRA6 Q16445 2/20 0.32
GABRG1 Q8N1C3 2/20 0.32
GABRG3 Q99928 2/20 0.32
GABRQ Q9UN88 2/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11722836 0.78
SCHEMBL332969 0.78 ALDH1A1 (0.35) ALDH1A1TSHRFGFR4GABRPGABRD
SCHEMBL717707 0.75
SCHEMBL26928513 0.75
SCHEMBL4114676 0.75
SCHEMBL2486910 0.75 GABRP (0.40) ALDH1A1TSHRFGFR4GABRPGABRD
SCHEMBL245241 0.73
SCHEMBL156118 0.73
SCHEMBL156117 0.73
SCHEMBL27641218 0.73 ALDH1A1 (0.50) ALDH1A1TSHRFGFR4LMNAOR51E2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0154343-B1 ADSORBENT Research Development Corporation of Japan (JP) 1991-06-19 EP claimed
EP-0731909-A4 SENSORS EMPLOYING INTERFERENCE OF ELECTROMAGNETIC WAVES PASSING THROUGH WAVEGUIDES HAVING FUNCTIONALIZED SURFACES OREGON STATE (US) 1997-09-03 EP disclosed
EP-0731909-A1 SENSORS EMPLOYING INTERFERENCE OF ELECTROMAGNETIC WAVES PASSING THROUGH WAVEGUIDES HAVING FUNCTIONALIZED SURFACES THE STATE OF OREGON ACTING BY AND THROUGH THE OREGON STATEBOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY (US) 1996-09-18 EP disclosed
US-5465151-A Sensors employing interference of electromagnetic waves passing through waveguides having functionalized surfaces STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF OREGON (US) 1995-11-07 US disclosed
WO-1994018544-A1 SENSORS EMPLOYING INTERFERENCE OF ELECTROMAGNETIC WAVES PASSING THROUGH WAVEGUIDES HAVING FUNCTIONALIZED SURFACES THE STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF OREGON (US) 1994-08-18 WO disclosed
US-4747956-A CROSSLINKED POLYAMINO ACID RESEARCH DEVELOPMENT CORPORATION (JP) 1988-05-31 US disclosed