SCHEMBL8928073

Cc1ccc(-c2cccc(OP(Oc3cccc(-c4ccc(C)cc4C(C)(C)C)c3-c3ccc(C)cc3C(C)(C)C)Oc3cccc(-c4ccc(C)cc4C(C)(C)C)c3-c3ccc(C)cc3C(C)(C)C)c2-c2ccc(C)cc2C(C)(C)C)c(C(C)(C)C)c1

nearest known ligand 0.32

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	MRGPRX4	Q96LA9	1/20	0.32

▸	POLB	P06746	1/20	0.31

▸	KDM4E	B2RXH2	2/20	0.30

▸	ALDH1A1	P00352	2/20	0.30

▸	F2	P00734	2/20	0.30

▸	MAPT	P10636	2/20	0.30

▸	ELANE	P08246	1/20	0.30

▸	XBP1	P17861	1/20	0.30

▸	HTT	P42858	1/20	0.30

▸	KMT2A	Q03164	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL6166149	0.89	MRGPRX4 (0.33)	MRGPRX4POLBALDH1A1
SCHEMBL11335841	0.86	NPC1 (0.37)	KDM4EALDH1A1
SCHEMBL690036	0.83	CA2 (0.34)	KDM4EALDH1A1MAPT
SCHEMBL10605858	0.79	ALDH1A1 (0.34)	POLBALDH1A1
SCHEMBL131793	0.76	ALDH1A1 (0.32)	ALDH1A1
SCHEMBL11335843	0.75	ALDH1A1 (0.36)	ALDH1A1MAPTHTTKMT2A
SCHEMBL5174545	0.74	ELANE (0.44)	POLBALDH1A1MAPTELANEHTT
SCHEMBL132991	0.74	ALDH1A1 (0.39)	MRGPRX4POLBKDM4EALDH1A1MAPT
SCHEMBL29367415	0.74	ALDH1A1 (0.39)	MRGPRX4POLBKDM4EALDH1A1MAPT
SCHEMBL20560117	0.74	PDK2 (0.33)	POLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5648554-A	GROUP 8 METAL PHOSPHITE COMPLEX CATALYST	MITSUBISHI CHEMICAL CORPORATION (JP)	1997-07-15	—	—	US	disclosed