Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.62 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928236 | 0.91 | MTNR1A (0.63) | MTNR1AMTNR1BCYP2D6 | |
| SCHEMBL18183659 | 0.89 | HPGD (0.63) | MTNR1AHPGDCYP2D6 | |
| SCHEMBL8928119 | 0.87 | MTNR1A (0.81) | MTNR1AMTNR1B | |
| SCHEMBL8928128 | 0.85 | MTNR1A (0.56) | MTNR1AMTNR1BCNR1CNR2 | |
| SCHEMBL8928067 | 0.84 | MTNR1A (0.74) | MTNR1AMTNR1B | |
| SCHEMBL8928060 | 0.81 | MTNR1A (0.79) | MTNR1AMTNR1B | |
| SCHEMBL21734283 | 0.80 | HPGD (0.59) | MTNR1AMTNR1BHPGDCYP2D6 | |
| SCHEMBL28000835 | 0.80 | HPGD (0.59) | MTNR1AMTNR1BHPGDCYP2D6 | |
| SCHEMBL12377082 | 0.80 | CHRM2 (0.54) | MTNR1AMTNR1BCYP2D6 | |
| SCHEMBL28569142 | 0.80 | CNR1 (0.58) | CYP2D6CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541228-A | Melatonergic agents | BRISTOL-MYERS SQUIBB CO. (US) | 1996-07-30 | — | — | US | claimed |
| EP-0706994-A1 | Melatonergic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-04-17 | — | — | EP | claimed |
| US-5661185-A | AN ALKOXYPHENYL-ALKYLUREA COMPOUND TREATING SLEEP DISORDER | BRISTOL-MYERS SQUIBB CO. (US) | 1997-08-26 | — | — | US | disclosed |
| US-5541228-A | Melatonergic agents | BRISTOL-MYERS SQUIBB CO. (US) | 1996-07-30 | — | — | US | disclosed |
| EP-0706994-A1 | Melatonergic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-04-17 | — | — | EP | disclosed |