Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | ACACB | O00763 | 1/20 | 0.48 |
| ▸ | ACACA | Q13085 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928236 | 0.86 | MTNR1A (0.63) | MTNR1AMTNR1B | |
| SCHEMBL8928079 | 0.85 | MTNR1A (0.62) | MTNR1AMTNR1BCNR1CNR2 | |
| SCHEMBL8928119 | 0.82 | MTNR1A (0.81) | MTNR1AMTNR1B | |
| SCHEMBL4568828 | 0.80 | PPARA (0.51) | CNR1CNR2 | |
| SCHEMBL18183659 | 0.79 | HPGD (0.63) | MTNR1A | |
| SCHEMBL8928067 | 0.79 | MTNR1A (0.74) | MTNR1AMTNR1B | |
| SCHEMBL8274392 | 0.78 | CNR1 (0.45) | MTNR1ACNR1CNR2 | |
| SCHEMBL3929685 | 0.77 | KDM5A (0.48) | MTNR1ACNR1CNR2ACACBACACA | |
| SCHEMBL8928060 | 0.76 | MTNR1A (0.79) | MTNR1AMTNR1B | |
| SCHEMBL2208238 | 0.76 | ACACB (0.49) | MTNR1AMTNR1BACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541228-A | Melatonergic agents | BRISTOL-MYERS SQUIBB CO. (US) | 1996-07-30 | — | — | US | claimed |
| EP-0706994-A1 | Melatonergic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-04-17 | — | — | EP | claimed |
| US-5661185-A | AN ALKOXYPHENYL-ALKYLUREA COMPOUND TREATING SLEEP DISORDER | BRISTOL-MYERS SQUIBB CO. (US) | 1997-08-26 | — | — | US | disclosed |
| US-5541228-A | Melatonergic agents | BRISTOL-MYERS SQUIBB CO. (US) | 1996-07-30 | — | — | US | disclosed |
| EP-0706994-A1 | Melatonergic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-04-17 | — | — | EP | disclosed |