Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 8/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928100 | 1.00 | MTNR1A (0.51) | MTNR1AMTNR1BCA12CA1CA2 | |
| SCHEMBL8928193 | 0.83 | MTNR1A (0.55) | MTNR1AMTNR1B | |
| SCHEMBL13853573 | 0.80 | CA12 (0.57) | MTNR1AMTNR1BCA12CA1CA2 | |
| SCHEMBL17150039 | 0.77 | CA12 (0.61) | MTNR1AMTNR1BCA12CA1CA2 | |
| SCHEMBL18183555 | 0.77 | CA12 (0.60) | MTNR1AMTNR1BCA12CA1CA2 | |
| SCHEMBL1009815 | 0.76 | MTNR1A (0.75) | MTNR1AMTNR1BCA12CA1CA2 | |
| SCHEMBL13570066 | 0.75 | ALOX5 (0.60) | CA12CA1CA2CA14 | |
| SCHEMBL16411820 | 0.75 | HPGD (0.50) | ADRB2HPGD | |
| SCHEMBL7281853 | 0.75 | CA12 (0.55) | CA12CA1CA2CA14 | |
| SCHEMBL28715271 | 0.75 | CA12 (0.50) | CA12CA1CA2CA14HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5661185-A | AN ALKOXYPHENYL-ALKYLUREA COMPOUND TREATING SLEEP DISORDER | BRISTOL-MYERS SQUIBB CO. (US) | 1997-08-26 | — | — | US | disclosed |
| US-5541228-A | Melatonergic agents | BRISTOL-MYERS SQUIBB CO. (US) | 1996-07-30 | — | — | US | disclosed |
| EP-0706994-A1 | Melatonergic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-04-17 | — | — | EP | disclosed |