SCHEMBL8928104

SCHEMBL8928104

COc1cccc(CCCNC(C)=O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 7/20 1.00
MTNR1B P49286 7/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8928132 0.96 MTNR1A (0.92) MTNR1AMTNR1B
SCHEMBL876345 0.91 MTNR1A (0.83) MTNR1AMTNR1B
SCHEMBL13725463 0.88 MTNR1A (0.79) MTNR1AMTNR1B
SCHEMBL8928126 0.87 MTNR1A (0.78) MTNR1AMTNR1B
SCHEMBL29991337 0.87 MTNR1A (0.77) MTNR1AMTNR1B
SCHEMBL28850813 0.87 MTNR1A (0.77) MTNR1AMTNR1B
SCHEMBL27867629 0.86 MTNR1A (0.80) MTNR1AMTNR1B
SCHEMBL8928085 0.86 MTNR1A (0.75) MTNR1AMTNR1B
SCHEMBL8928118 0.86 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL3397753 0.85 MTNR1A (0.73) MTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5541228-A Melatonergic agents BRISTOL-MYERS SQUIBB CO. (US) 1996-07-30 US claimed
EP-0706994-A1 Melatonergic agents BRISTOL-MYERS SQUIBB COMPANY (US) 1996-04-17 EP claimed
EP-4662319-A2 PERSONALIZED CRISPR PROFILING FOR CANCER Integrate Bioscience LLC (US) 2025-12-17 EP disclosed
WO-2024168301-A2 PERSONALIZED CRISPR PROFILING FOR CANCER FUNCTION ONCOLOGY, INC. (US) 2024-08-15 WO disclosed
CN-1118464-C Noval pyrimidine derivatives and process and preparing thereof YUHAN CORP (KR) 2003-08-20 CN disclosed
CN-1251586-A Noval pyrimidine derivatives and process and preparing thereof YUHAN CORP (KR) 2000-04-26 CN disclosed
US-5661185-A AN ALKOXYPHENYL-ALKYLUREA COMPOUND TREATING SLEEP DISORDER BRISTOL-MYERS SQUIBB CO. (US) 1997-08-26 US disclosed
EP-0573464-B1 PROCESS FOR PREPARING TRANS-PIPERIDINE-2,5-DICARBOXYLATES PFIZER (US) 1997-03-19 EP disclosed
US-5541228-A Melatonergic agents BRISTOL-MYERS SQUIBB CO. (US) 1996-07-30 US disclosed
EP-0706994-A1 Melatonergic agents BRISTOL-MYERS SQUIBB COMPANY (US) 1996-04-17 EP disclosed