Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.51 |
| ▸ | RPS6KA4 | O75676 | 2/20 | 0.51 |
| ▸ | PRKACA | P17612 | 2/20 | 0.51 |
| ▸ | GSK3B | P49841 | 2/20 | 0.51 |
| ▸ | PRKX | P51817 | 2/20 | 0.51 |
| ▸ | PRKG1 | Q13976 | 2/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.51 |
| ▸ | GSK3A | P49840 | 1/20 | 0.51 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.51 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.51 |
| ▸ | SGK2 | Q9HBY8 | 1/20 | 0.51 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | FDPS | P14324 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27342817 | 1.00 | ECE1 (0.52) | ECE1KDM4EROCK2ROCK1MAPK1 | |
| SCHEMBL27503053 | 0.87 | ACACB (0.48) | ECE1KDM4EROCK2ROCK1MAPK1 | |
| SCHEMBL6192467 | 0.87 | ACACB (0.48) | ECE1KDM4EROCK2ROCK1MAPK1 | |
| SCHEMBL14114760 | 0.84 | CYP3A4 (0.52) | ECE1KDM4EROCK2ROCK1MAPK1 | |
| SCHEMBL2973301 | 0.82 | MAPK1 (0.68) | KDM4EROCK2ROCK1MAPK1RPS6KA5 | |
| SCHEMBL3897966 | 0.82 | MAPK1 (0.68) | KDM4EROCK2ROCK1MAPK1RPS6KA5 | |
| SCHEMBL3959317 | 0.82 | MAPK1 (0.68) | KDM4EROCK2ROCK1MAPK1RPS6KA5 | |
| SCHEMBL28938948 | 0.82 | ECE1 (0.47) | ECE1KDM4ENAPRTCYP3A4FDPS | |
| SCHEMBL6192681 | 0.81 | ROCK2 (0.59) | ECE1ROCK2ROCK1MAPK1RPS6KA5 | |
| SCHEMBL27529142 | 0.81 | ALDH1A1 (0.46) | ECE1KDM4EROCK2ROCK1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101646427-A | Inhibitors of akt activity | SMITHKLINE BEECHAM CORP US | 2010-02-10 | — | — | CN | disclosed |
| EP-0495269-B1 | Thermosetting reactive resin mixture, moulded article and coating made therefrom | DAINIPPON INK & CHEMICALS (JP) | 1997-03-05 | — | — | EP | disclosed |
| US-5292833-A | Polyepoxide compound, carbamate compound and catalyst | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1994-03-08 | — | — | US | disclosed |
| WO-1992012192-A2 | THERMOSETTING REACTIVE RESIN MIXTURE, MOULDED ARTICLE AND COATING MADE THEREFROM | DAINIPPON INK & CHEMICALS, INC. (JP) | 1992-07-23 | — | — | WO | disclosed |
| EP-0495269-A2 | Thermosetting reactive resin mixture, moulded article and coating made therefrom | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1992-07-22 | — | — | EP | disclosed |