Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | PTPRB | P23467 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928353 | 0.82 | PPARA (0.36) | PPARAPPARGCTSSCA1CA2 | |
| SCHEMBL8928375 | 0.79 | NR1D1 (0.47) | PPARAMAPTPPARG | |
| SCHEMBL8059351 | 0.78 | PPARA (0.46) | PPARAPPARGCTSSNPSR1L3MBTL1 | |
| SCHEMBL8387845 | 0.77 | — | — | |
| SCHEMBL6432521 | 0.74 | PPARA (0.43) | PPARAPPARGLTA4HCTSSCA1 | |
| SCHEMBL6429868 | 0.72 | PPARA (0.43) | PPARAPPARGLTA4HCTSSCA1 | |
| SCHEMBL8693590 | 0.71 | CA1 (0.54) | EGFRAURKBMAPTTDP1TLR7 | |
| SCHEMBL23572300 | 0.69 | EPOR (0.41) | PPARACTSSCA1CA2SMN1; SMN2 | |
| SCHEMBL7666444 | 0.69 | ATM (0.40) | MAPTTDP1CTSSCA1 | |
| SCHEMBL7511620 | 0.69 | CTSS (0.40) | CTSSCA1CA2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5649537-A | CONJUGATION OF A BILE ACID WITH A CHELATING AGENT AND BI- OR TRIVALENT METALS; IMAGING OF THE HEPTATOBILIARY SYSTEM; NUCLEAR MAGNETIC RESONANCE | DIBRA S.P.A. (IT) | 1997-07-22 | — | — | US | disclosed |