SCHEMBL8928454

SCHEMBL8928454

NS(=O)(=O)c1cc(O)c2c(NC(=O)c3ccccc3)cc(S(N)(=O)=O)cc2c1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ APEX1 P27695 1/20 0.81
▸ CA2 P00918 6/20 0.54
▸ CA1 P00915 5/20 0.54
▸ CA9 Q16790 5/20 0.54
▸ CA12 O43570 3/20 0.54
▸ MAOA P21397 1/20 0.49
▸ ENPP2 Q13822 1/20 0.48
▸ PLK1 P53350 4/20 0.47
▸ MAPT P10636 2/20 0.47
▸ RAB9A P51151 1/20 0.47
▸ MEN1 O00255 1/20 0.46
▸ PSMD14 O00487 1/20 0.46
▸ POLB P06746 1/20 0.46
▸ RECQL P46063 1/20 0.46
▸ CACNA1B Q00975 1/20 0.46
▸ APBA1 Q02410 1/20 0.46
▸ KMT2A Q03164 1/20 0.46
▸ CTDSP1 Q9GZU7 1/20 0.46
▸ SAE1 Q9UBE0 1/20 0.46
▸ UBA2 Q9UBT2 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9411865 0.89 APEX1 (1.00) APEX1CA2CA1CA9CA12
SCHEMBL1413131 0.89 APEX1 (1.00) APEX1CA2CA1CA9CA12
SCHEMBL9411862 0.87 APEX1 (0.77) APEX1CA2CA1CA9CA12
SCHEMBL11508852 0.82 APEX1 (0.84) APEX1ENPP2MAPTRAB9AMEN1
SCHEMBL11593854 0.80 APEX1 (0.81) APEX1MAOAENPP2RAB9AMEN1
SCHEMBL11589917 0.79 APEX1 (0.77) APEX1CA2CA1CA9CA12
SCHEMBL13619183 0.79 APEX1 (0.81) APEX1ENPP2RAB9AMEN1RECQL
SCHEMBL6560534 0.79 APEX1 (0.77) APEX1CA2CA1CA9CA12
SCHEMBL5567709 0.79 APEX1 (0.76) APEX1MAOAENPP2MAPTMEN1
SCHEMBL10904451 0.78 APEX1 (0.79) APEX1ENPP2RAB9AMEN1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5691099-A DISCOLORATION INHIBITION; PRESERVATION; IMAGE QUALITY RICOH COMPANY, LTD. (JP) 1997-11-25 — — US disclosed
US-5556733-A COUPLER RICOH COMPANY, LTD. (JP) 1996-09-17 — — US disclosed
US-5478689-A With coupler contained in microcapsules made of alkali-soluble resin RICOH COMPANY, LTD. (JP) 1995-12-26 — — US disclosed
US-4497887-A Thermal development type diazo copying material with hydrophobic resin encapsulated coupler particle Ricoh Compay, Ltd. (JP) 1985-02-05 — — US disclosed
US-4467024-A Process for the production of thermo-developable type diazo copying material RICOH CO., LTD. (JP) 1984-08-21 — — US disclosed
US-4416967-A SUBSTRATE, PRECOAT LAYER OF SILICA AND COPOLYMER OF ACRYLIC, OXY, RICOH CO., LTD. (JP) 1983-11-22 — — US disclosed
US-4400456-A FATTY ACID AMIDE COLOR ASSIST, HIGH DENSITY IMAGES RICOH CO., LTD. (JP) 1983-08-23 — — US disclosed
Send feedback