Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | PTAFR | P25105 | 16/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928421 | 0.92 | OPRK1 (0.57) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL8928523 | 0.91 | PTAFR (0.49) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL8928549 | 0.90 | MIF (0.43) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL8928627 | 0.87 | MIF (0.42) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL8928601 | 0.87 | PTAFR (0.44) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL8928615 | 0.85 | OPRK1 (0.55) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL8928639 | 0.85 | OPRK1 (0.55) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL8928499 | 0.84 | OPRK1 (0.53) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL8928543 | 0.84 | OPRK1 (0.44) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL8928848 | 0.84 | OPRK1 (0.44) | OPRK1PDE4DMIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776892-A1 | THIENYLAZOLE COMPOUND AND THIENOTRIAZOLODIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |