Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | CCKBR | P32239 | 5/20 | 0.38 |
| ▸ | CCKAR | P32238 | 4/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | TSPO | P30536 | 1/20 | 0.38 |
| ▸ | GLP1R | P43220 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928590 | 0.94 | OPRK1 (0.46) | OPRK1PDE4DMIFRECQLSMN1; SMN2 | |
| SCHEMBL8928421 | 0.91 | OPRK1 (0.57) | OPRK1PDE4DMIF | |
| SCHEMBL8928679 | 0.91 | MIF (0.45) | OPRK1MIFRECQLSMN1; SMN2HPGD | |
| SCHEMBL8928781 | 0.86 | MIF (0.46) | OPRK1MIFRECQLSMN1; SMN2HPGD | |
| SCHEMBL8928523 | 0.85 | PTAFR (0.49) | OPRK1PDE4DMIF | |
| SCHEMBL8928615 | 0.84 | OPRK1 (0.55) | OPRK1PDE4DMIF | |
| SCHEMBL8928487 | 0.84 | OPRK1 (0.46) | OPRK1PDE4DMIF | |
| SCHEMBL8928636 | 0.84 | MIF (0.44) | OPRK1MIFDRD2DRD3HTR2C | |
| SCHEMBL8928639 | 0.84 | OPRK1 (0.55) | OPRK1PDE4DDRD2DRD3 | |
| SCHEMBL8928499 | 0.83 | OPRK1 (0.53) | OPRK1PDE4DDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776892-A1 | THIENYLAZOLE COMPOUND AND THIENOTRIAZOLODIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |