Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CCKAR | P32238 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTAFR | P25105 | 9/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.34 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928561 | 0.92 | RECQL (0.38) | MEN1CCKARKMT2AHPGDRECQL | |
| SCHEMBL8928748 | 0.91 | OPRK1 (0.42) | MEN1CCKARKMT2AHPGDRECQL | |
| SCHEMBL8928637 | 0.88 | MEN1 (0.42) | MEN1CCKARKMT2AHPGDRECQL | |
| SCHEMBL8928876 | 0.87 | MEN1 (0.37) | MEN1CCKARKMT2AHPGDRECQL | |
| SCHEMBL8928672 | 0.86 | OPRK1 (0.43) | MEN1CCKARKMT2AHPGDRECQL | |
| SCHEMBL8928766 | 0.85 | OPRK1 (0.42) | MEN1CCKARKMT2AHPGDRECQL | |
| SCHEMBL8928442 | 0.83 | OPRK1 (0.54) | MEN1CCKARKMT2APTAFROPRK1 | |
| SCHEMBL8928668 | 0.83 | PTAFR (0.38) | MEN1CCKARKMT2AHPGDPTAFR | |
| SCHEMBL8928710 | 0.82 | RECQL (0.38) | MEN1CCKARKMT2AHPGDRECQL | |
| SCHEMBL8928679 | 0.81 | MIF (0.45) | CCKARHPGDRECQLSMN1; SMN2OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776892-A1 | THIENYLAZOLE COMPOUND AND THIENOTRIAZOLODIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |