Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CCKAR | P32238 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 6/20 | 0.35 |
| ▸ | BRD2 | P25440 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 6/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928429 | 0.92 | MEN1 (0.35) | MEN1KMT2AHPGDRECQLSMN1; SMN2 | |
| SCHEMBL8928678 | 0.87 | MEN1 (0.39) | MEN1KMT2ACCKARHPGDRECQL | |
| SCHEMBL8928748 | 0.84 | OPRK1 (0.42) | MEN1KMT2ACCKARHPGDRECQL | |
| SCHEMBL8928637 | 0.84 | MEN1 (0.42) | MEN1KMT2ACCKARHPGDRECQL | |
| SCHEMBL8928869 | 0.83 | L3MBTL1 (0.36) | MEN1KMT2ACCKARBRD4BRD2 | |
| SCHEMBL8928636 | 0.81 | MIF (0.44) | BRD4 | |
| SCHEMBL8928672 | 0.80 | OPRK1 (0.43) | MEN1KMT2ACCKARHPGDRECQL | |
| SCHEMBL8928561 | 0.80 | RECQL (0.38) | MEN1KMT2ACCKARHPGDRECQL | |
| SCHEMBL8928404 | 0.79 | HPGD (0.41) | HPGDRECQLSMN1; SMN2BRD4BRD2 | |
| SCHEMBL8928766 | 0.79 | OPRK1 (0.42) | MEN1KMT2ACCKARHPGDRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776892-A1 | THIENYLAZOLE COMPOUND AND THIENOTRIAZOLODIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |