Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL27560437 | 1.00 | — | — | |
| Alcohol SCHEMBL3099525 | 1.00 | TSHR (0.50) | TSHRALDH1A1ATMATRSMN1; SMN2 | |
| Alcohol SCHEMBL10748456 | 0.96 | TSHR (0.46) | TSHRALDH1A1ATMATRSMN1; SMN2 | |
| Alcohol SCHEMBL28328836 | 0.96 | TSHR (0.46) | TSHRALDH1A1ATMATRSMN1; SMN2 | |
| Propane SCHEMBL27770056 | 0.96 | TSHR (0.46) | TSHRALDH1A1ATMATRSMN1; SMN2 | |
| Alcohol SCHEMBL10522243 | 0.96 | TSHR (0.46) | TSHRALDH1A1ATMATRSMN1; SMN2 | |
| Alcohol SCHEMBL6886787 | 0.93 | TSHR (0.43) | TSHRALDH1A1ATMATR | |
| Propane SCHEMBL7026177 | 0.87 | TSHR (0.42) | TSHRALDH1A1ATMATRSMN1; SMN2 | |
| Propane SCHEMBL11720454 | 0.87 | TSHR (0.42) | TSHRALDH1A1ATMATRSMN1; SMN2 | |
| Propane SCHEMBL7566447 | 0.87 | TSHR (0.42) | TSHRALDH1A1ATMATRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019160694-A1 | METHOD AND SYSTEM FOR TAGGING LEATHER OR HIDES TREATED WITH BIOCIDE AND IDENTIFYING SAME | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 2019-08-22 | — | — | WO | claimed |
| CN-104710644-B | A kind of method that antimicrobial surface is prepared on medical macromolecular materials surface | 中国科学院长春应用化学研究所 | 2017-09-22 | — | — | CN | claimed |
| CN-113976304-A | Beneficiation method for comprehensively recovering tungsten tin bismuth silicon from skarn type tin tailings | 广东省科学院资源利用与稀土开发研究所 | 2022-01-28 | — | — | CN | disclosed |
| CN-108636613-B | A kind of N, N- dialkyl group-S- hydroxyalkyl-dithiocarbamate collector and the preparation method and application thereof | 中南大学 | 2019-10-18 | — | — | CN | disclosed |
| CN-109310110-A | Hydroxyl methionine analogs preparation suitable for Specialty Chemical application | 诺华丝国际股份有限公司 | 2019-02-05 | — | — | CN | disclosed |
| CN-108636613-A | A kind of N, N- dialkyl group-S- hydroxyalkyls-dithiocarbamate collector and the preparation method and application thereof | 中南大学 | 2018-10-12 | — | — | CN | disclosed |
| CN-104710644-B | A kind of method that antimicrobial surface is prepared on medical macromolecular materials surface | 中国科学院长春应用化学研究所 | 2017-09-22 | — | — | CN | disclosed |
| CN-102875484-A | Preparation method of 1-ethoxyl-5-sulfydryl-1H-tetrazolium | JIANGXI JINDUN BIOLOG TECHNOLOGY CO LTD | 2013-01-16 | — | — | CN | disclosed |
| US-5663004-A | IMAGE RECORDING SHEETS WITH FUNGICIDES, RECEIVERS AND COATINGS | XEROX CORPORATION (US) | 1997-09-02 | — | — | US | disclosed |
| US-4645661-A | Method for alleviating cisplatin-induced nephrotoxicity and dithiocarbamate compounds for effecting same | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 1987-02-24 | — | — | US | disclosed |