Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL27560437 | 1.00 | — | — | |
| Alcohol SCHEMBL8928828 | 1.00 | TSHR (0.50) | TSHRALDH1A1ATMATRSMN1; SMN2 | |
| Alcohol SCHEMBL10748456 | 0.96 | TSHR (0.46) | TSHRALDH1A1ATMATRSMN1; SMN2 | |
| Alcohol SCHEMBL28328836 | 0.96 | TSHR (0.46) | TSHRALDH1A1ATMATRSMN1; SMN2 | |
| Propane SCHEMBL27770056 | 0.96 | TSHR (0.46) | TSHRALDH1A1ATMATRSMN1; SMN2 | |
| Alcohol SCHEMBL10522243 | 0.96 | TSHR (0.46) | TSHRALDH1A1ATMATRSMN1; SMN2 | |
| Alcohol SCHEMBL6886787 | 0.93 | TSHR (0.43) | TSHRALDH1A1ATMATR | |
| Propane SCHEMBL7026177 | 0.87 | TSHR (0.42) | TSHRALDH1A1ATMATRSMN1; SMN2 | |
| Propane SCHEMBL11720454 | 0.87 | TSHR (0.42) | TSHRALDH1A1ATMATRSMN1; SMN2 | |
| Propane SCHEMBL7566447 | 0.87 | TSHR (0.42) | TSHRALDH1A1ATMATRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060240489-A1 | Carbodithioate ligands for nanotechnology and biosensing applications | NATIONAL SCIENCE FOUNDATION | 2006-10-26 | — | — | US | claimed |
| CN-116547090-A | Composition comprising silver nanoplates | 巴斯夫欧洲公司 | 2023-08-04 | — | — | CN | disclosed |
| CN-116507686-A | UV-VIS radiation curable security ink for producing dichroic security features | 锡克拜控股有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-111449077-B | Metiram compound bactericide and application thereof | 北京联合大学 | 2021-06-08 | — | — | CN | disclosed |
| CN-111449077-A | Metiram compound bactericide and application thereof | 北京联合大学 | 2020-07-28 | — | — | CN | disclosed |
| US-7803568-B2 | Carbodithioate ligands for nanotechnology and biosensing applications | PURDUE RESEARCH FOUNDATION (US) | 2010-09-28 | — | — | US | disclosed |
| US-20080124776-A1 | Carbodithioate Ligands For Nanotechnology and Methods of Use | NATIONAL SCIENCE FOUNDATION | 2008-05-29 | — | — | US | disclosed |
| US-20060240489-A1 | Carbodithioate ligands for nanotechnology and biosensing applications | NATIONAL SCIENCE FOUNDATION | 2006-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060240489-A1 | Carbodithioate ligands for nanotechnology and biosensing applications | SPR, ICMT, TST | TSHR 629/4885ALDH1A1 971/4885ATM 3517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.