Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL10748456 | 1.00 | TSHR (0.46) | TSHRALDH1A1ATMATRSMN1; SMN2 | |
| Alcohol SCHEMBL6886787 | 0.96 | TSHR (0.43) | TSHRALDH1A1ATMATR | |
| Alcohol SCHEMBL27560437 | 0.96 | — | — | |
| Alcohol SCHEMBL3099525 | 0.96 | TSHR (0.50) | TSHRALDH1A1ATMATRSMN1; SMN2 | |
| Alcohol SCHEMBL8928828 | 0.96 | TSHR (0.50) | TSHRALDH1A1ATMATRSMN1; SMN2 | |
| Propane SCHEMBL27770056 | 0.92 | TSHR (0.46) | TSHRALDH1A1ATMATRSMN1; SMN2 | |
| Alcohol SCHEMBL28328836 | 0.92 | TSHR (0.46) | TSHRALDH1A1ATMATRSMN1; SMN2 | |
| Propane SCHEMBL11778447 | 0.88 | TSHR (0.39) | TSHRALDH1A1ATMATRSMN1; SMN2 | |
| Alcohol SCHEMBL28815494 | 0.85 | ALDH1A1 (0.33) | TSHRALDH1A1 | |
| Butane SCHEMBL10694152 | 0.85 | TSHR (0.36) | TSHRALDH1A1ATMATRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4806393-A | OVERCOATING WITH DITHIOCARBAMATE CROSSLINKED POLYVINYL CHLORIDE | YEDA RESEARCH AND DEVELOPMENT COMPANY LIMITED (IL) | 1989-02-21 | — | — | US | claimed |