SCHEMBL892987

SCHEMBL892987

C(#CCN1CCCC1)CN1CCCC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 1.00
CHRM1 P11229 9/20 0.58
CHRM2 P08172 8/20 0.58
CHRM4 P08173 8/20 0.58
CHRM5 P08912 8/20 0.58
CHRM3 P20309 8/20 0.58
CYP1A2 P05177 1/20 0.54
CYP2D6 P10635 1/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
MEN1 O00255 1/20 0.48
ALDH1A1 P00352 1/20 0.48
KMT2A Q03164 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3757253 0.97 LMNA (0.93) LMNACHRM1CHRM2CHRM4CHRM5
SCHEMBL9733197 0.97 LMNA (0.93) LMNACHRM1CHRM2CHRM4CHRM5
Hydrochloric Acid SCHEMBL6081619 0.97 LMNA (0.93) LMNACHRM1CHRM2CHRM4CHRM5
Hydrochloric Acid SCHEMBL9093331 0.97 LMNA (0.93) LMNACHRM1CHRM2CHRM4CHRM5
SCHEMBL3162750 0.87 LMNA (0.77) LMNACHRM1CHRM2CHRM4CHRM5
SCHEMBL1467165 0.86 LMNA (0.74) LMNACHRM1CHRM2CHRM4CHRM5
SCHEMBL4476489 0.86 LMNA (0.74) LMNACHRM1CHRM2CHRM4CHRM5
SCHEMBL964866 0.86 LMNA (0.74) LMNACHRM1CHRM2CHRM4CHRM5
SCHEMBL5279915 0.86 LMNA (0.74) LMNACHRM1CHRM2CHRM4CHRM5
SCHEMBL3168002 0.84 LMNA (0.72) LMNACHRM1CHRM2CHRM4CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 303 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118048412-B Preparation method of aspergillus fumigatus tremorine C 青岛普瑞迈生物工程有限公司 2024-12-10 CN claimed
US-20240336977-A1 MICRORNA-REGULATED BIOMARKERS AND DRUG TARGETS FOR IMPROVING DIAGNOSIS AND TREATMENT OF LUNG OR BREAST CANCER West Virginia University Board of Governors on behalf of West Virginia University (US) 2024-10-10 US claimed
CN-118090975-A Method for simultaneously measuring multiple mycotoxins in biodegradable food contact material 南宁海关技术中心 2024-05-28 CN claimed
CN-118048412-A Preparation method of aspergillus fumigatus tremorine C 青岛普瑞迈生物工程有限公司 2024-05-17 CN claimed
CN-110669801-B Method for improving content of tremorine in secondary metabolite of Festuca sinensis-endophytic fungi strain PA 兰州大学 2022-02-01 CN claimed
CN-111655856-A Modular DNA assembly system 维多利亚联结有限公司 2020-09-11 CN claimed
CN-110669801-A Method for improving content of tremorine in secondary metabolite of Festuca sinensis-endophytic fungi strain PA 兰州大学 2020-01-10 CN claimed
CN-106526167-A Penitrem A combined antigen as well as preparation and application of antibody of antigen 中国农业大学 2017-03-22 CN claimed
US-20140100198-A1 ENZYME INHIBITING COMPOUNDS AND METHODS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2014-04-10 US claimed
EP-2665739-A1 METHODS AND COMPOSITIONS RELATED TO SYNERGISTIC RESPONSES TO ONCOGENIC MUTATIONS THE UNIVERSITY OF ROCHESTER (US) 2013-11-27 EP claimed
EP-2188630-A2 METHODS AND COMPOSITIONS RELATED TO SYNERGISTIC RESPONSES TO ONCOGENIC MUTATIONS THE UNIVERSITY OF ROCHESTER (US) 2010-05-26 EP claimed
WO-2009045443-A2 METHODS AND COMPOSITIONS RELATED TO SYNERGISTIC RESPONSES TO ONCOGENIC MUTATIONS THE UNIVERSITY OF ROCHESTER (US) 2009-04-09 WO claimed
CN-101224207-A Medicine for inducing autophagy and treating disease caused by wrong unfolded protein aggregation, and filtration method thereof SHANGHAI INST ORGANIC CHEM (CN) 2008-07-23 CN claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
EP-0673782-B1 Recording sheets containing pyrrole, pyrrolidine, pyridine, piperidine, homopiperidine, quinoline, isoquinoline, quinuclidine, indole, and indazole compounds XEROX CORP (US) 2000-06-14 EP claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140100198-A1 ENZYME INHIBITING COMPOUNDS AND METHODS COASY, FADS2, FDPS LMNA 3983/4885CHRM1 4092/4885CHRM2 4725/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.