SCHEMBL8929880

SCHEMBL8929880

COC12CC3[C]C(CC(C3)C1)C2

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.34
HSD11B1 P28845 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL727714 0.80 NPSR1 (0.48) NPSR1HSD11B1
SCHEMBL15148891 0.68 NPSR1 (0.34) NPSR1HSD11B1
SCHEMBL15149246 0.67 NPSR1 (0.33) NPSR1HSD11B1
SCHEMBL12861222 0.67 JAK2 (0.34) NPSR1HSD11B1
SCHEMBL12861242 0.67 JAK2 (0.34) NPSR1HSD11B1
SCHEMBL2716449 0.67 JAK2 (0.34) NPSR1HSD11B1
SCHEMBL6901718 0.65 NPSR1 (0.39) NPSR1HSD11B1
SCHEMBL2986988 0.65 HSD11B1 (0.33) NPSR1HSD11B1
SCHEMBL1397649 0.65 NPSR1 (0.46) NPSR1HSD11B1
SCHEMBL31497777 0.65 NPSR1 (0.32) NPSR1HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5605795-A Assays using chemiluminescent, enzymatically cleavable substituted 1,2-dioxetanes and kits therefor TROPIX, INC. (US) 1997-02-25 US disclosed
US-5220005-A Reactable with enzyme to release optically detectable energy TROPIX, INC. (US) 1993-06-15 US disclosed