Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8930175 | 0.86 | MAPK1 (0.35) | MTNR1AMTNR1BHSD17B10MAPK1MEN1 | |
| SCHEMBL8929999 | 0.83 | MTNR1A (0.34) | MTNR1AMTNR1BHSD17B10MAPK1MEN1 | |
| SCHEMBL3805634 | 0.73 | MAPK1 (0.51) | HSD17B10MAPK1MEN1KMT2ANPC1 | |
| SCHEMBL8930182 | 0.70 | MAPK1 (0.39) | MTNR1AMTNR1BHSD17B10MAPK1MEN1 | |
| SCHEMBL8930172 | 0.69 | MAPK1 (0.35) | MTNR1AMTNR1BHSD17B10MAPK1MEN1 | |
| SCHEMBL8930176 | 0.69 | MAPK1 (0.35) | MTNR1AMTNR1BHSD17B10MAPK1MEN1 | |
| SCHEMBL183844 | 0.66 | — | — | |
| SCHEMBL3967541 | 0.58 | MAPK1 (0.51) | HSD17B10MAPK1MEN1KMT2ANPC1 | |
| SCHEMBL11632854 | 0.58 | MAPK1 (0.30) | MAPK1 | |
| SCHEMBL11488683 | 0.58 | MAPK1 (0.40) | HSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693827-A | Treatment of HIV infections and compounds useful therein | UNIROYAL CHEMICAL COMPANY, INC. | 1997-12-02 | — | — | US | disclosed |