Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 15/20 | 1.00 |
| ▸ | DRD3 | P35462 | 15/20 | 1.00 |
| ▸ | DRD4 | P21917 | 8/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 2/20 | 1.00 |
| ▸ | HTR1A | P08908 | 1/20 | 1.00 |
| ▸ | ADRB2 | P07550 | 1/20 | 1.00 |
| ▸ | CASP1 | P29466 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 0.97 |
| ▸ | MAPT | P10636 | 1/20 | 0.97 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.75 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.75 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.75 |
| ▸ | TSHR | P16473 | 1/20 | 0.75 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.75 |
| ▸ | FYN | P06241 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29460204 | 1.00 | DRD2 (1.00) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL29448457 | 1.00 | DRD2 (1.00) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL7568447 | 1.00 | DRD2 (1.00) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL623950 | 1.00 | DRD2 (1.00) | DRD2DRD3DRD4MEN1KMT2A | |
| Bromide SCHEMBL4204027 | 0.99 | DRD2 (1.00) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL7499793 | 0.94 | DRD2 (0.89) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL28381701 | 0.91 | DRD2 (0.83) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL28381702 | 0.91 | DRD2 (0.83) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL10074634 | 0.88 | DRD2 (0.79) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL9585366 | 0.88 | DRD2 (0.85) | DRD2DRD3DRD4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9002973-A | — | — | None | — | — | JP | disclosed |
| JP-H092973-A | VOMIT-INDUCING AGENT AND INDUCTION OF VOMITING | DAINIPPON PHARMACEUT CO LTD | 1997-01-07 | — | — | JP | disclosed |