SCHEMBL623950

SCHEMBL623950

CCCN(CCC)C1CCc2ccc(O)cc2C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 15/20 1.00
DRD3 P35462 15/20 1.00
DRD4 P21917 8/20 1.00
MEN1 O00255 3/20 1.00
KMT2A Q03164 3/20 1.00
CYP2D6 P10635 2/20 1.00
HTR1A P08908 1/20 1.00
ADRB2 P07550 1/20 1.00
CASP1 P29466 1/20 1.00
LMNA P02545 2/20 0.97
MAPT P10636 1/20 0.97
ALDH1A1 P00352 1/20 0.75
CYP1A2 P05177 1/20 0.75
CYP2C9 P11712 1/20 0.75
TSHR P16473 1/20 0.75
CYP2C19 P33261 1/20 0.75
FYN P06241 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8930123 1.00 DRD2 (1.00) DRD2DRD3DRD4MEN1KMT2A
SCHEMBL29460204 1.00 DRD2 (1.00) DRD2DRD3DRD4MEN1KMT2A
SCHEMBL29448457 1.00 DRD2 (1.00) DRD2DRD3DRD4MEN1KMT2A
SCHEMBL7568447 1.00 DRD2 (1.00) DRD2DRD3DRD4MEN1KMT2A
Bromide SCHEMBL4204027 0.99 DRD2 (1.00) DRD2DRD3DRD4MEN1KMT2A
SCHEMBL7499793 0.94 DRD2 (0.89) DRD2DRD3DRD4MEN1KMT2A
SCHEMBL28381701 0.91 DRD2 (0.83) DRD2DRD3DRD4MEN1KMT2A
SCHEMBL28381702 0.91 DRD2 (0.83) DRD2DRD3DRD4MEN1KMT2A
SCHEMBL10074634 0.88 DRD2 (0.79) DRD2DRD3DRD4MEN1KMT2A
SCHEMBL9585366 0.88 DRD2 (0.85) DRD2DRD3DRD4MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025024501-A1 NEUROMODULATORY PEPTIDES LACTOCORE, INC. (US) 2025-01-30 WO claimed
US-20220072042-A1 METHODS FOR IMPROVED IMMUNOTHERAPY LEVITE MIA (IL) 2022-03-10 US claimed
US-20180177760-A1 COMPOSITIONS COMPRISING BIOREVERSIBLE DERIVATIVES OF HYDROXY N-SUBSTITUTED-2-AMINOTETRALINS, AND RELATED DOSAGE FORMS SPRIASO LLC (US) 2018-06-28 US claimed
WO-2016014242-A1 COMPOSITIONS COMPRISING BIOREVERSIBLE DERIVATIVES OF HYDROXY N-SUBSTITUTED-2-AMINOTETRALINS, DOSAGE FORMS, AND RELATED METHODS SPRIASO LLC (US) 2016-01-28 WO claimed
US-20160015684-A1 COMPOSITIONS COMPRISING BIOREVERSIBLE DERIVATIVES OF HYDROXY N- SUBSTITUTED-2-AMINOTETRALINS, DOSAGE FORMS, AND RELATED METHODS SPRIASO LLC 2016-01-21 US claimed
US-20160016887-A1 Methods of treating a subject using bioreversible derivatives of hydroxy n-substituted-2-aminotetralins SPRIASO LLC 2016-01-21 US claimed
EP-2049129-B1 CATECHOLAMINE RECEPTOR MODULATION YEDA RES & DEV (IL) 2013-06-12 EP claimed
US-8241903-B2 Catecholamine receptor modulation YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 2012-08-14 US claimed
US-20120164139-A1 Dopamine 3 receptor agonist and antagonist treatment of gastrointestinal motility disorders THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2012-06-28 US claimed
US-20100099669-A1 Dopamine 3 receptor agonist and antagonist treatment of gastrointestinal motility disorders PASRICHA PANKAJ JAY 2010-04-22 US claimed
US-20090176705-A1 MODULAR PLATFORM FOR TARGETED THERAPEUTIC DELIVERY WASHINGTON UNIVERSITY (US) 2009-07-09 US claimed
US-20060116350-A1 Dopamine 3 receptor agonist and antagonist treatment of gastrointestinal motility disorders BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM, THE 2006-06-01 US claimed
WO-2004050065-A1 INTRAOCULAR DELIVERY COMPOSITIONS AND METHODS BIOSANTE PHARMACEUTICALS, INC. (US) 2004-06-17 WO claimed
US-20030185892-A1 Intraocular delivery compositions and methods BIOSANTE PHARMACEUTICALS, INC. 2003-10-02 US claimed
JP-10279404-A None JP disclosed
US-20260137691-A1 WB3 FOR ANESTHESIA AND TREATING PAIN PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2026-05-21 US disclosed
US-12611412-B2 Targeting the TLK1/NEK1 axis in prostate cancer BOARD OF SUPERVISORS OF LOUISANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2026-04-28 US disclosed
WO-1990015047-A1 THERAPEUTICALLY USEFUL 2-AMINOTETRALIN DERIVATIVES THE UPJOHN COMPANY (US) 1990-12-13 WO disclosed
WO-1990007490-A1 HALO SUBSTITUTED AMINOTETRALINS THE UPJOHN COMPANY (US) 1990-07-12 WO disclosed
WO-1989009050-A1 THERAPEUTICALLY USEFUL TETRALIN DERIVATIVES THE UPJOHN COMPANY (US) 1989-10-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160016887-A1 Methods of treating a subject using bioreversible derivatives of hydroxy n-substituted-2-aminotetralins SLC7A1, CYP2D6, SLC19A1 DRD2 1496/4885DRD3 1430/4885DRD4 1516/4885
US-20160015684-A1 COMPOSITIONS COMPRISING BIOREVERSIBLE DERIVATIVES OF HYDROXY N- SUBSTITUTED-2-AMINOTETRALINS, DOSAGE FORMS, AND RELATED METHODS SLC7A1, CYP2D6, CYP3A7 DRD2 1602/4885DRD3 1564/4885DRD4 1742/4885
US-20260137691-A1 WB3 FOR ANESTHESIA AND TREATING PAIN WNT3, TRPV3, ADRB3 DRD2 1584/4885DRD3 253/4885DRD4 2066/4885
US-20180177760-A1 COMPOSITIONS COMPRISING BIOREVERSIBLE DERIVATIVES OF HYDROXY N-SUBSTITUTED-2-AMINOTETRALINS, AND RELATED DOSAGE FORMS SLC7A1, CYP2D6, CYP3A7 DRD2 1234/4885DRD3 1281/4885DRD4 1474/4885
US-20090176705-A1 MODULAR PLATFORM FOR TARGETED THERAPEUTIC DELIVERY SIGMAR1, TMEM97, CCAR2 DRD2 520/4885DRD3 1869/4885DRD4 1451/4885
US-12611412-B2 Targeting the TLK1/NEK1 axis in prostate cancer NEK5, NEK3, PLK3 DRD2 1737/4885DRD3 1355/4885DRD4 2105/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.