SCHEMBL8930167

SCHEMBL8930167

CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@](N)(O)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.71

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
USP2 O75604 2/20 0.71
CYP46A1 Q9Y6A2 2/20 0.71
LMNA P02545 1/20 0.71
ABCB1 P08183 1/20 0.71
OSBP P22059 1/20 0.71
RORC P51449 1/20 0.71
OSBP2 Q969R2 1/20 0.71
GRIN1 Q05586 15/20 0.66
GRIN2B Q13224 15/20 0.66
GRIN2A Q12879 13/20 0.65
POLA1 P09884 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL466045 1.00 USP2 (0.71) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL28057984 1.00 USP2 (0.71) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL4961477 0.90 GRIN1 (0.80) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL5935410 0.90 GRIN1 (0.80) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL103515 0.90 USP2 (0.74) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL932623 0.90 USP2 (0.74) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL2185461 0.90 USP2 (0.74) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL720338 0.89 USP2 (0.71) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL18529717 0.89 USP2 (0.71) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL10943687 0.89 USP2 (0.71) USP2CYP46A1LMNAABCB1OSBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105879107-A Antimycotic polymerisable bone cement and a method for the production thereof 贺利氏医疗有限责任公司 2016-08-24 CN claimed
US-4839175-A USING CHOLESTEROL DERIVATIVES; FOR OPTHALMIC DRUG DELIVERY LIPOSOME TECHNOLOGY, INC. (US) 1989-06-13 US claimed
EP-0316345-A1 LIPOSOMES WITH ENHANCED RETENTION ON MUCOSAL TISSUE LIPOSOME TECHNOLOGY, INC. (US) 1989-05-24 EP claimed
EP-0316345-A4 LIPOSOMES WITH ENHANCED RETENTION ON MUCOSAL TISSUE. LIPOSOME TECHNOLOGY INC (US) 1989-05-16 EP claimed
US-4804539-A Ophthalmic liposomes LIPOSOME TECHNOLOGY, INC. (US) 1989-02-14 US claimed
WO-1988000824-A1 LIPOSOMES WITH ENHANCED RETENTION ON MUCOSAL TISSUE LIPOSOME TECHNOLOGY, INC. (US) 1988-02-11 WO claimed
US-4496482-A FROM ISOCYANATOSILANES, FOR BONDING TO SUBSTRATES UNION CARBIDE CORPORATION (US) 1985-01-29 US claimed
CN-111698991-A Inhibitors of protease activated receptor-2 武田药品工业株式会社 2020-09-22 CN disclosed
US-9931430-B2 Antimycotic polymerisable bone cement and a method for the production thereof HERAEUS MEDICAL GMBH (DE) 2018-04-03 US disclosed
CN-105879107-A Antimycotic polymerisable bone cement and a method for the production thereof 贺利氏医疗有限责任公司 2016-08-24 CN disclosed
US-20160235883-A1 Antimycotic Polymerisable Bone Cement and a Method for the Production Thereof HERAEUS MEDICAL GMBH (DE) 2016-08-18 US disclosed
US-20140004499-A1 BIOSURFACE ENGINEERING BOVIN NICOLAI VLADIMIROVICH (RU) 2014-01-02 US disclosed
WO-2012099477-A1 BIOSURFACE ENGINEERING BOVIN NICOLAI VLADIMIROVICH (RU) 2012-07-26 WO disclosed
US-4839175-A USING CHOLESTEROL DERIVATIVES; FOR OPTHALMIC DRUG DELIVERY LIPOSOME TECHNOLOGY, INC. (US) 1989-06-13 US disclosed
EP-0316345-A1 LIPOSOMES WITH ENHANCED RETENTION ON MUCOSAL TISSUE LIPOSOME TECHNOLOGY, INC. (US) 1989-05-24 EP disclosed
EP-0316345-A4 LIPOSOMES WITH ENHANCED RETENTION ON MUCOSAL TISSUE. LIPOSOME TECHNOLOGY INC (US) 1989-05-16 EP disclosed
US-4804539-A Ophthalmic liposomes LIPOSOME TECHNOLOGY, INC. (US) 1989-02-14 US disclosed
WO-1988000824-A1 LIPOSOMES WITH ENHANCED RETENTION ON MUCOSAL TISSUE LIPOSOME TECHNOLOGY, INC. (US) 1988-02-11 WO disclosed
US-4496482-A FROM ISOCYANATOSILANES, FOR BONDING TO SUBSTRATES UNION CARBIDE CORPORATION (US) 1985-01-29 US disclosed
US-4316041-A BOND TO GLASS UNION CARBIDE CORPORATION (US) 1982-02-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140004499-A1 BIOSURFACE ENGINEERING SGMS1, SGMS2, LSS USP2 3094/4885CYP46A1 244/4885LMNA 1095/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.