SCHEMBL8930253

SCHEMBL8930253

CC(C)OCC(C)C(=O)OC(C)C.CCOC(=O)C(C)COC(C)C

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.35
CYP2C19 P33261 1/20 0.35
ALDH1A1 P00352 3/20 0.34
GAA P10253 2/20 0.34
LMNA P02545 3/20 0.33
HSD17B10 Q99714 1/20 0.33
TSHR P16473 1/20 0.33
ALOX15 P16050 1/20 0.32
MGAM O43451 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
SOAT1 P35610 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL443632 0.92 ALDH1A1 (0.40) CYP3A4CYP2C19ALDH1A1GAALMNA
SCHEMBL444489 0.90 TSHR (0.40) LMNATSHRALOX15
SCHEMBL7697129 0.79 TSHR (0.35) CYP3A4CYP2C19ALDH1A1GAATSHR
SCHEMBL10405112 0.78 TSHR (0.37) ALDH1A1GAALMNAHSD17B10TSHR
SCHEMBL10404892 0.76 HSD17B10 (0.35) ALDH1A1LMNAHSD17B10TSHR
SCHEMBL29115716 0.74 ALDH1A1 (0.39) ALDH1A1GAALMNAHSD17B10ALOX15
SCHEMBL29115715 0.74 ALDH1A1 (0.39) ALDH1A1GAALMNAHSD17B10ALOX15
SCHEMBL446187 0.73 ALDH1A1 (0.47) CYP2C19ALDH1A1LMNATSHRL3MBTL1
SCHEMBL12150115 0.73 ALDH1A1 (0.55) CYP3A4CYP2C19ALDH1A1GAALMNA
SCHEMBL445591 0.73 ALDH1A1 (0.42) CYP3A4CYP2C19ALDH1A1GAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5612303-A HYDROXY OR ETHERIFIED ESTERS NITTO CHEMICAL INDUSTRY CO., LTD. (JP) 1997-03-18 US disclosed