Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 14/20 | 0.75 |
| ▸ | EGFR | P00533 | 12/20 | 0.75 |
| ▸ | ABL1 | P00519 | 9/20 | 0.75 |
| ▸ | ABL2 | P42684 | 9/20 | 0.75 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.65 |
| ▸ | LCK | P06239 | 4/20 | 0.62 |
| ▸ | KDR | P35968 | 4/20 | 0.62 |
| ▸ | TEK | Q02763 | 3/20 | 0.62 |
| ▸ | LYN | P07948 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | RGS12 | O14924 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | GMNN | O75496 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | FYN | P06241 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8930246 | 0.93 | SRC (0.74) | SRCEGFRABL1ABL2RIPK2 | |
| SCHEMBL132510 | 0.86 | SRC (1.00) | SRCEGFRABL1ABL2RIPK2 | |
| SCHEMBL5936173 | 0.85 | SRC (0.97) | SRCEGFRABL1ABL2RIPK2 | |
| SCHEMBL6460652 | 0.85 | LCK (0.74) | SRCEGFRABL1LCKKDR | |
| SCHEMBL24458572 | 0.80 | LCK (0.77) | SRCEGFRABL1LCKKDR | |
| SCHEMBL8320765 | 0.78 | SRC (0.75) | SRCEGFRABL1ABL2RIPK2 | |
| Hydrochloric Acid SCHEMBL7023167 | 0.78 | SRC (0.85) | SRCEGFRABL1ABL2RIPK2 | |
| SCHEMBL6467053 | 0.78 | LCK (0.81) | SRCEGFRABL1LCKKDR | |
| SCHEMBL6870684 | 0.77 | SRC (0.77) | SRCEGFRABL1ABL2RIPK2 | |
| Hydrochloric Acid SCHEMBL7098308 | 0.77 | SRC (0.85) | SRCEGFRABL1ABL2RIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997028161-A1 | NOVEL PYRROLO[2,3-D]PYRIMIDINES AND THEIR USE AS TYROSINE KINASE INHIBITORS | NOVARTIS AG (CH) | 1997-08-07 | — | — | WO | disclosed |