Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 7/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30644916 | 1.00 | KDM4E (0.61) | KDM4EALDH1A1LMNAGPR35POLB | |
| SCHEMBL530998 | 0.86 | GPR35 (0.68) | KDM4EALDH1A1GPR35POLBHPGD | |
| SCHEMBL14405907 | 0.86 | MAOB (0.60) | KDM4EALDH1A1LMNAGPR35MAPT | |
| SCHEMBL13494165 | 0.85 | MAOB (0.58) | KDM4EALDH1A1GPR35MAPTMEN1 | |
| SCHEMBL13494158 | 0.84 | MAOB (0.61) | KDM4EALDH1A1LMNAGPR35MAPT | |
| SCHEMBL15084990 | 0.81 | TSHR (0.49) | KDM4EALDH1A1LMNAGPR35MAOB | |
| SCHEMBL13494164 | 0.81 | KDM4E (0.57) | KDM4EALDH1A1GPR35MEN1HPGD | |
| SCHEMBL14405916 | 0.80 | KDM4E (0.54) | KDM4EALDH1A1GPR35HPGDMAOB | |
| SCHEMBL15082533 | 0.79 | TSHR (0.66) | KDM4EALDH1A1LMNAGPR35MEN1 | |
| SCHEMBL1406180 | 0.77 | MAOB (0.64) | KDM4EALDH1A1MAPTHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12372526-B2 | Method for identifying modulators of G3BP activity | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2025-07-29 | — | — | US | claimed |
| US-20220091120-A1 | METHOD FOR IDENTIFYING MODULATORS OF G3BP ACTIVITY | ST. JUDE CHILDREN'S RESEARCH HOSPITAL | 2022-03-24 | — | — | US | claimed |
| US-8487078-B2 | Kinase and phosphatase assays | Life Technologies Corporation (US) | 2013-07-16 | — | — | US | claimed |
| US-8409814-B2 | Sensor proteins and assay methods | Life Technologies Corporation (US) | 2013-04-02 | — | — | US | claimed |
| EP-2192192-B1 | Kinase and phosphatase assays | LIFE TECHNOLOGIES CORP (US) | 2012-10-03 | — | — | EP | claimed |
| US-20120083427-A1 | KINASE AND PHOSPHATASE ASSAYS | Life Technologies Corporation (US) | 2012-04-05 | — | — | US | claimed |
| US-8067536-B2 | Kinase and phosphatase assays | Life Technologies Corporation (US) | 2011-11-29 | — | — | US | claimed |
| US-20110111422-A1 | SENSOR PROTEINS AND ASSAY METHODS | Life Technologies Corporation (US) | 2011-05-12 | — | — | US | claimed |
| US-20100240080-A1 | KINASE AND PHOSPHATASE ASSAYS | Life Technologies Corporation (US) | 2010-09-23 | — | — | US | claimed |
| EP-2192192-A1 | Kinase and phosphatase assays | Life Technologies Corporation (US) | 2010-06-02 | — | — | EP | claimed |
| US-20080213811-A1 | SENSOR PROTEINS AND ASSAY METHODS | INVITROGEN CORPORATION (US) | 2008-09-04 | — | — | US | claimed |
| EP-1664332-A4 | KINASE AND PHOSPHATASE ASSAYS | INVITROGEN CORP (US) | 2008-05-14 | — | — | EP | claimed |
| US-20070059787-A1 | Kinase and phosphatase assays | INVITROGEN CORPORATION (US) | 2007-03-15 | — | — | US | claimed |
| EP-1671128-A2 | MULTIPLEX BINDING AND ACTIVITY ASSAYS | INVITROGEN CORPORATION (US) | 2006-06-21 | — | — | EP | claimed |
| EP-1664332-A2 | KINASE AND PHOSPHATASE ASSAYS | INVITROGEN CORPORATION (US) | 2006-06-07 | — | — | EP | claimed |
| US-20050170442-A1 | Bimolecular optical probes | Life Technologies Corporation | 2005-08-04 | — | — | US | claimed |
| WO-2005026730-A2 | MULTIPLEX BINDING AND ACTIVITY ASSAYS | INVITROGEN CORPORATION (US) | 2005-03-24 | — | — | WO | claimed |
| US-20050064485-A1 | Multiplex binding and activity assays | Life Technologies Corporation | 2005-03-24 | — | — | US | claimed |
| US-20050054573-A1 | Kinase and phosphatase assays | Life Technologies Corporation | 2005-03-10 | — | — | US | claimed |
| WO-2005012329-A2 | KINASE AND PHOSPHATASE ASSAYS | INVITROGEN CORPORATION (US) | 2005-02-10 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050054573-A1 | Kinase and phosphatase assays | PACSIN2, PNKP, ACP1 | KDM4E 2000/4885ALDH1A1 4741/4885LMNA 1952/4885 |
| US-20120083427-A1 | KINASE AND PHOSPHATASE ASSAYS | PTMS, ACP1, PPME1 | KDM4E 1271/4885ALDH1A1 4743/4885LMNA 1852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.