SCHEMBL8930465

SCHEMBL8930465

CCCCOC(=O)C=Cc1ccccc1C

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.54
APP P05067 5/20 0.53
KDM4E B2RXH2 2/20 0.51
ALDH1A1 P00352 2/20 0.51
HCAR2 Q8TDS4 2/20 0.49
HPGD P15428 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
TSHR P16473 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
ALOX5 P09917 1/20 0.45
ESR1 P03372 2/20 0.45
AKR1B10 O60218 1/20 0.44
AKR1B1 P15121 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8930462 1.00 ATM (0.54) ATMAPPKDM4EALDH1A1HCAR2
SCHEMBL5174853 0.94 APP (0.55) ATMAPPKDM4EALDH1A1HCAR2
SCHEMBL28658552 0.91 APP (0.51) APPKDM4EALDH1A1HCAR2HPGD
SCHEMBL29975450 0.90 ATM (0.50) ATMAPPKDM4EALDH1A1HCAR2
SCHEMBL1897277 0.86 CA12 (0.54) ATMKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL1897276 0.86 CA12 (0.54) ATMKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL11834908 0.85 APP (0.60) ATMAPPKDM4EALDH1A1HCAR2
SCHEMBL19244396 0.85 KDM4E (0.61) ATMAPPKDM4EALDH1A1HCAR2
SCHEMBL3940920 0.85 APP (0.60) ATMAPPKDM4EALDH1A1HCAR2
SCHEMBL18843944 0.85 ATM (0.54) ATMAPPKDM4EALDH1A1HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2909130-B1 CATALYSIS BY METAL NANOPARTICLES DISPERSED WITHIN A HIERARCHICALLY POROUS CARBON MATERIAL BAKKER MARTIN (US) 2022-01-26 EP disclosed
CN-103509562-B Crystal aligning agent, liquid crystal orienting film, phase retardation film, the manufacture method of phase retardation film, liquid crystal display cells and polymer JSR株式会社 2017-08-04 CN disclosed
US-9669388-B2 Catalysis by metal nanoparticles dispersed within a hierarchically porous carbon material The Board Trustees of The University of Alabama (US) 2017-06-06 US disclosed
US-20160089657-A1 CATALYSIS BY METAL NANOPARTICLES DISPERSED WITHIN A HIERARCHICALLY POROUS CARBON MATERIAL THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA 2016-03-31 US disclosed
US-9233366-B2 Catalysis by metal nanoparticles dispersed within a hierarchically porous carbon material BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) 2016-01-12 US disclosed
US-20140107371-A1 CATALYSIS BY METAL NANOPARTICLES DISPERSED WITHIN A HIERARCHICALLY POROUS CARBON MATERIAL BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) 2014-04-17 US disclosed
US-5698755-A Process for preparing aromatic olefins using palladacycle catalysis HOECHST AG (DE) 1997-12-16 US disclosed
EP-0301587-A1 Liquid crystal compounds and intermediates thereof WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1989-02-01 EP disclosed
EP-0094432-A1 LIQUID CRYSTAL DISPLAY UNIT SONY CORPORATION (JP) 1983-11-23 EP disclosed