Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CCNC | P24863 | 1/20 | 0.48 |
| ▸ | CDK8 | P49336 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1897277 | 1.00 | CA12 (0.54) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10783189 | 0.91 | CA12 (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11054639 | 0.89 | CA12 (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28658552 | 0.89 | APP (0.51) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5752920 | 0.89 | CA12 (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5752922 | 0.89 | CA12 (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8930465 | 0.86 | ATM (0.54) | ESR1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8930462 | 0.86 | ATM (0.54) | ESR1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2391128 | 0.85 | MAPT (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8423203 | 0.85 | CA12 (0.53) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116239103-A | Carbon dot, preparation method thereof and photocatalytic hydroboration method | 中国石油大学(华东) | 2023-06-09 | — | — | CN | claimed |
| US-20250051299-A1 | PRODUCTION METHOD FOR FLUOROMETHYL DERIVATIVE | DAIKIN INDUSTRIES, LTD. (JP) | 2025-02-13 | — | — | US | disclosed |
| US-12162854-B2 | Production method for fluoromethyl derivative | DAIKIN INDUSTRIES, LTD. (JP) | 2024-12-10 | — | — | US | disclosed |
| CN-117623924-A | Preparation method and application of trisubstituted olefin | 苏州新启材料科技有限公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-116239103-A | Carbon dot, preparation method thereof and photocatalytic hydroboration method | 中国石油大学(华东) | 2023-06-09 | — | — | CN | disclosed |
| CN-110248971-B | Copolymer and optical film using the same | 东曹株式会社 | 2021-11-02 | — | — | CN | disclosed |
| CN-113135816-A | Method for synthesizing photoactive bromohydrin compound | 常州大学 | 2021-07-20 | — | — | CN | disclosed |
| US-9994554-B2 | Barbiturate and thiobarbiturate compounds for use in cancer therapy | NUHOPE LLC (US) | 2018-06-12 | — | — | US | disclosed |
| US-9994554-B2 | Barbiturate and thiobarbiturate compounds for use in cancer therapy | NUHOPE LLC (US) | 2018-06-12 | — | — | US | disclosed |
| US-20180134691-A1 | BARBITURATE AND THIOBARBITURATE COMPOUNDS FOR USE IN CANCER THERAPY | NUHOPE, LLC (US) | 2018-05-17 | — | — | US | disclosed |
| US-7935830-B2 | Tricyclic indeno-pyrrole derivatives as serotonin receptor modulators | ATHERSYS, INC. (US) | 2011-05-03 | — | — | US | disclosed |
| US-20100210680-A1 | TRICYCLIC HETEROCYCLIC DERIVATIVES | N.V. ORGANON | 2010-08-19 | — | — | US | disclosed |
| US-20090239925-A1 | TRICYCLIC INDENO-PYRROLE DERIVATIVES AS SEROTONIN RECEPTOR MODULATORS | ATHERSYS, INC. | 2009-09-24 | — | — | US | disclosed |
| EP-1841738-A2 | TRICYCLIC INDENO-PYRROLE DERIVATIVES AS SEROTONIN RECEPTOR MODULATORS | Athersys, Inc. (US) | 2007-10-10 | — | — | EP | disclosed |
| WO-2007081299-A2 | TRICYCLIC INDENO-PYRROLE DERIVATIVES AS SEROTONIN RECEPTOR MODULATORS | ATHERSYS, INC. (US) | 2007-07-19 | — | — | WO | disclosed |
| US-20060025601-A1 | Tricyclic indeno-pyrrole derivatives as serotonin receptor modulators | ATHERSYS, INC. | 2006-02-02 | — | — | US | disclosed |
| US-6211197-B1 | CARBOXYLIC ACID OR TETRAZOLE DERIVATES; ANALGESICS, ANTIPYRETICS, AND ANTIINFLAMMATORY AGENTS; SIDE EFFECT REDUCTION | MERCK FROSST CANADA & CO. (CA) | 2001-04-03 | — | — | US | disclosed |
| EP-1056728-A1 | DIHYDRO-BENZO(1,4)OXAZINES AND TETRAHYDROQUINOXALINES | Aventis Pharma Limited (GB) | 2000-12-06 | — | — | EP | disclosed |
| WO-2000039103-A1 | DIHYDRO-BENZO(1,4)OXAZINES AND TETRAHYDROQUINOXALINES | AVENTIS PHARMA LIMITED (GB) | 2000-07-06 | — | — | WO | disclosed |
| US-4335054-A | Process for the preparation of alkenylbenzenecarboxylic acid derivatives and alkenylnaphthalenecarboxylic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1982-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210680-A1 | TRICYCLIC HETEROCYCLIC DERIVATIVES | TPH1, HTR2C, TPH2 | CA12 4325/4885CA1 2907/4885CA2 4712/4885 |
| US-20180134691-A1 | BARBITURATE AND THIOBARBITURATE COMPOUNDS FOR USE IN CANCER THERAPY | MGMT, BCL2, BAX | CA12 2523/4885CA1 1085/4885CA2 2713/4885 |
| US-20060025601-A1 | Tricyclic indeno-pyrrole derivatives as serotonin receptor modulators | HTR5A, HTR3E, HTR1E | CA12 4862/4885CA1 4852/4885CA2 4622/4885 |
| US-20090239925-A1 | TRICYCLIC INDENO-PYRROLE DERIVATIVES AS SEROTONIN RECEPTOR MODULATORS | HTR5A, HTR3E, HTR1E | CA12 4862/4885CA1 4852/4885CA2 4622/4885 |
| US-12162854-B2 | Production method for fluoromethyl derivative | AFF1, AFF2, ROS1 | CA12 2264/4885CA1 3273/4885CA2 3030/4885 |
| US-20250051299-A1 | PRODUCTION METHOD FOR FLUOROMETHYL DERIVATIVE | AFF1, AFF2, ROS1 | CA12 2264/4885CA1 3273/4885CA2 3030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.