Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC28A1 | O00337 | 1/20 | 0.45 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.45 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.45 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.45 |
| ▸ | P2RY14 | Q15391 | 6/20 | 0.38 |
| ▸ | P2RY2 | P41231 | 5/20 | 0.34 |
| ▸ | P2RY6 | Q15077 | 8/20 | 0.34 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29049894 | 0.87 | SLC28A1 (0.44) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY14 | |
| SCHEMBL6002015 | 0.81 | SLC28A1 (0.50) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY14 | |
| SCHEMBL12658269 | 0.81 | SLC28A1 (0.50) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY14 | |
| SCHEMBL42133 | 0.81 | SLC28A1 (0.50) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY14 | |
| Ammonia Solution, Strong SCHEMBL28145131 | 0.80 | SLC28A1 (0.49) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY14 | |
| Hydrogen Sulfide SCHEMBL28043850 | 0.80 | SLC28A1 (0.49) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY14 | |
| SCHEMBL27355175 | 0.80 | TK1 (0.40) | — | |
| SCHEMBL30514301 | 0.80 | SLC28A1 (0.51) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY14 | |
| SCHEMBL425154 | 0.79 | SLC28A1 (0.50) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY14 | |
| SCHEMBL19666777 | 0.79 | SLC28A1 (0.50) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0549615-A4 | SUGAR MODIFIED OLIGONUCLEOTIDES THAT DETECT AND MODULATE GENE EXPRESSION | ISIS PHARMACEUTICALS INC (US) | 1997-08-27 | — | — | EP | disclosed |
| EP-0549615-A1 | SUGAR MODIFIED OLIGONUCLEOTIDES THAT DETECT AND MODULATE GENE EXPRESSION | ISIS PHARMACEUTICALS, INC. (US) | 1993-07-07 | — | — | EP | disclosed |
| WO-1992003568-A1 | SUGAR MODIFIED OLIGONUCLEOTIDES THAT DETECT AND MODULATE GENE EXPRESSION | ISIS PHARMACEUTICALS, INC. (US) | 1992-03-05 | — | — | WO | disclosed |