Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | TYMP | P19971 | 1/20 | 0.38 |
| ▸ | TK2 | O00142 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7256295 | 0.90 | TK1 (0.39) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL14785922 | 0.85 | PYGM (0.35) | LMNATYMPTK2 | |
| SCHEMBL3079827 | 0.84 | PYGM (0.34) | TK1LMNATK2 | |
| SCHEMBL3079836 | 0.83 | TK2 (0.52) | TK1BLMTK2 | |
| SCHEMBL8904559 | 0.81 | TK1 (0.43) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL1825757 | 0.81 | TK1 (0.43) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL12658380 | 0.81 | TK1 (0.43) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL8930585 | 0.80 | SLC28A1 (0.45) | — | |
| SCHEMBL16042097 | 0.80 | TK1 (0.42) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL29041599 | 0.80 | TK1 (0.42) | TK1ALDH1A1LMNAALBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1059213-C | Preparation of d4T from 5-methyluridine | BRISTOL MYERS SQUIBB CO (US) | 2000-12-06 | — | — | CN | claimed |
| CN-1147519-A | Preparation of d4T from 5-methyluridine | BRISTOL MYERS SQUIBB CO (US) | 1997-04-16 | — | — | CN | claimed |
| CN-1195770-C | Preparation of d4T from 5-methyl uridine | BRISTOL MYERS SQIBB CO (US) | 2005-04-06 | — | — | CN | disclosed |
| CN-1059213-C | Preparation of d4T from 5-methyluridine | BRISTOL MYERS SQUIBB CO (US) | 2000-12-06 | — | — | CN | disclosed |
| CN-1270172-A | Preparation of d4T from 5-methyl uridine | BRISTOL MYERS SQIBB CO (US) | 2000-10-18 | — | — | CN | disclosed |
| CN-1055477-C | Intermediate compound for synthesizing nucleoside derivative | BRISTOL MYERS SQUIBB CO (US) | 2000-08-16 | — | — | CN | disclosed |
| CN-1040115-C | Large scale production of 2 ', 3 ' -didehydro-3 ' -deoxythymidine (d4T) using 5-methyluridine | BRISTOL MYERS SQUIBB CO (US) | 1998-10-07 | — | — | CN | disclosed |
| CN-1193021-A | Intermediate compound for synthesizing nucleoside derivative | BRISTOL MYERS SQIBB CO (US) | 1998-09-16 | — | — | CN | disclosed |
| CN-1147519-A | Preparation of d4T from 5-methyluridine | BRISTOL MYERS SQUIBB CO (US) | 1997-04-16 | — | — | CN | disclosed |
| CN-1112123-A | Large scale production of 2 ', 3 ' -didehydro-3 ' -deoxythymidine (d4T) using 5-methyluridine | BRISTOL MYERS SQUIBB CO (US) | 1995-11-22 | — | — | CN | disclosed |