Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25237701 | 1.00 | AOC3 (0.50) | AOC3SMN1; SMN2RIPK1SLC6A4SLC6A2 | |
| SCHEMBL10504562 | 0.81 | SMN1; SMN2 (0.40) | AOC3SMN1; SMN2RIPK1SLC6A4SLC6A2 | |
| SCHEMBL6666755 | 0.80 | AOC3 (0.52) | AOC3SMN1; SMN2RIPK1SLC6A4SLC6A2 | |
| SCHEMBL487167 | 0.79 | CYP3A4 (0.47) | RIPK1CYP3A4CYP2D6ALDH1A1ALOX15 | |
| SCHEMBL28365356 | 0.79 | ALDH1A1 (0.44) | SLC6A4CYP3A4CYP2D6ALDH1A1ALOX15 | |
| SCHEMBL17660057 | 0.79 | AOC3 (0.55) | AOC3SMN1; SMN2RIPK1SLC6A4SLC6A2 | |
| SCHEMBL2364517 | 0.79 | AOC3 (0.55) | AOC3SMN1; SMN2RIPK1SLC6A4SLC6A2 | |
| SCHEMBL16015530 | 0.79 | AOC3 (0.55) | AOC3SMN1; SMN2RIPK1SLC6A4SLC6A2 | |
| SCHEMBL28600445 | 0.78 | CYP2D6 (0.42) | AOC3RIPK1SLC6A4CYP3A4CYP2D6 | |
| SCHEMBL28932421 | 0.78 | SLC6A4 (0.50) | AOC3RIPK1SLC6A4CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9000280-A | — | — | None | — | — | JP | disclosed |
| JP-H09280-A | PRODUCTION OF (1R,2S)-1-PHENYL-1,2-PROPANEDIOL | ASAHI BREWERIES LTD | 1997-01-07 | — | — | JP | disclosed |