Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 3/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2512343 | 0.89 | L3MBTL1 (0.65) | L3MBTL1HTTTSHRMAPTLMNA | |
| SCHEMBL12227206 | 0.88 | MAPT (0.66) | L3MBTL1HTTTSHRMAPTLMNA | |
| Ethylene SCHEMBL27874359 | 0.88 | L3MBTL1 (0.64) | L3MBTL1HTTTSHRMAPTLMNA | |
| SCHEMBL28914785 | 0.88 | L3MBTL1 (0.64) | L3MBTL1HTTTSHRMAPTLMNA | |
| SCHEMBL5530375 | 0.88 | L3MBTL1 (0.64) | L3MBTL1HTTTSHRMAPTLMNA | |
| SCHEMBL12227200 | 0.88 | L3MBTL1 (0.64) | L3MBTL1HTTTSHRMAPTLMNA | |
| SCHEMBL30080354 | 0.88 | L3MBTL1 (0.64) | L3MBTL1HTTTSHRMAPTLMNA | |
| SCHEMBL12227212 | 0.88 | L3MBTL1 (0.64) | L3MBTL1HTTTSHRMAPTLMNA | |
| SCHEMBL13009640 | 0.87 | L3MBTL1 (0.62) | L3MBTL1HTTTSHRMAPTLMNA | |
| SCHEMBL31164658 | 0.86 | L3MBTL1 (0.62) | L3MBTL1HTTTSHRMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8785627-B2 | Copolymerizable methine and anthraquinone compounds and articles containing them | Abbott Medical Optics Inc. (US) | 2014-07-22 | — | — | US | disclosed |
| US-8501890-B2 | Copolymerizable methine and anthraquinone compounds and articles containing them | Abbott Medical Optics Inc. (US) | 2013-08-06 | — | — | US | disclosed |
| US-8501890-B2 | Copolymerizable methine and anthraquinone compounds and articles containing them | Abbott Medical Optics Inc. (US) | 2013-08-06 | — | — | US | disclosed |
| US-8360576-B2 | Copolymerizable methine and anthraquinone compounds and articles containing them | Abbott Medical Optics Inc. (US) | 2013-01-29 | — | — | US | disclosed |
| US-8360576-B2 | Copolymerizable methine and anthraquinone compounds and articles containing them | Abbott Medical Optics Inc. (US) | 2013-01-29 | — | — | US | disclosed |
| US-20130018159-A1 | COPOLYMERIZABLE METHINE AND ANTHRAQUINONE COMPOUNDS AND ARTICLES CONTAINING THEM | Abbott Medical Optics Inc. (US) | 2013-01-17 | — | — | US | disclosed |
| US-8188203-B2 | Intraocular lens formed from a polymer of an unsaturated aryl monoazo dye containing a 2-pyrazolin-5-one, dimedone (5,5-dimethyl-1,3-cyclohexanedione), acetoacetamide, malonamide, barbituric acid or 1,3-propanedione residue; yellow light absorbers; block ultraviolet and/or violet-blue light transmission | Abbott Medical Optics Inc. (US) | 2012-05-29 | — | — | US | disclosed |
| US-8188203-B2 | Intraocular lens formed from a polymer of an unsaturated aryl monoazo dye containing a 2-pyrazolin-5-one, dimedone (5,5-dimethyl-1,3-cyclohexanedione), acetoacetamide, malonamide, barbituric acid or 1,3-propanedione residue; yellow light absorbers; block ultraviolet and/or violet-blue light transmission | Abbott Medical Optics Inc. (US) | 2012-05-29 | — | — | US | disclosed |
| US-20110098322-A1 | PREPARATION OF NOVEL 1,3-SUBSTITUTED UREAS AS INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-04-28 | — | — | US | disclosed |
| US-20090076235-A1 | COPOLYMERIZABLE METHINE AND ANTHRAQUINONE COMPOUNDS AND ARTICLES CONTAINING THEM | Johnson & Johnson Surgical Vision, Inc. | 2009-03-19 | — | — | US | disclosed |
| US-20090076235-A1 | COPOLYMERIZABLE METHINE AND ANTHRAQUINONE COMPOUNDS AND ARTICLES CONTAINING THEM | Johnson & Johnson Surgical Vision, Inc. | 2009-03-19 | — | — | US | disclosed |
| US-20080182957-A1 | Copolymerizable azo compounds and articles containing them | Johnson & Johnson Surgical Vision, Inc. | 2008-07-31 | — | — | US | disclosed |
| US-20080182957-A1 | Copolymerizable azo compounds and articles containing them | Johnson & Johnson Surgical Vision, Inc. | 2008-07-31 | — | — | US | disclosed |
| US-7326423-B2 | Copolymerizable azo compounds and articles containing them | ADVANCED MEDICAL OPTICS, INC. (US) | 2008-02-05 | — | — | US | disclosed |
| US-7326423-B2 | Copolymerizable azo compounds and articles containing them | ADVANCED MEDICAL OPTICS, INC. (US) | 2008-02-05 | — | — | US | disclosed |
| US-7179308-B2 | Ethylenically-unsaturated blue anthraquinone dyes | EASTMAN CHEMICAL COMPANY (US) | 2007-02-20 | — | — | US | disclosed |
| US-7179308-B2 | Ethylenically-unsaturated blue anthraquinone dyes | EASTMAN CHEMICAL COMPANY (US) | 2007-02-20 | — | — | US | disclosed |
| US-7172634-B2 | Ethylenically-unsaturated blue anthraquinone dyes | EASTMAN CHEMICAL COMPANY (US) | 2007-02-06 | — | — | US | disclosed |
| US-7172634-B2 | Ethylenically-unsaturated blue anthraquinone dyes | EASTMAN CHEMICAL COMPANY (US) | 2007-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098322-A1 | PREPARATION OF NOVEL 1,3-SUBSTITUTED UREAS AS INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | EPHX1, EPHX2, NCEH1 | L3MBTL1 4807/4885HTT 4749/4885TSHR 4710/4885 |
| US-20130018159-A1 | COPOLYMERIZABLE METHINE AND ANTHRAQUINONE COMPOUNDS AND ARTICLES CONTAINING THEM | CRY1, AAAS, CYBA | L3MBTL1 4426/4885HTT 1017/4885TSHR 4322/4885 |
| US-20090076235-A1 | COPOLYMERIZABLE METHINE AND ANTHRAQUINONE COMPOUNDS AND ARTICLES CONTAINING THEM | AAAS, IK, CYBA | L3MBTL1 4550/4885HTT 605/4885TSHR 4166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.