SCHEMBL8930717

SCHEMBL8930717

CCOC(=O)c1c2c(c(C(c3c4c(c(C(=O)OCC)c5c3OC(C)(C)O5)OC(C)(C)O4)c3c4c(c(C(=O)OCC)c5c3OC(C)(C)O5)OC(C)(C)O4)c3c1OC(C)(C)O3)OC(C)(C)O2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.39
LMNA P02545 4/20 0.39
HPGD P15428 3/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
MAPT P10636 3/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39
GAA P10253 1/20 0.39
CYP3A4 P08684 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
NR1H2 P55055 1/20 0.38
NR1H3 Q13133 1/20 0.38
MAPK1 P28482 1/20 0.37
PDE4D Q08499 1/20 0.37
FHIT P49789 1/20 0.36
KMT2A Q03164 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7514575 0.77 CYP3A4 (0.45) ALDH1A1HPGDSMN1; SMN2MAPTCA12
SCHEMBL12530071 0.77 HPGD (0.45) ALDH1A1LMNAHPGDSMN1; SMN2MAPT
SCHEMBL8930681 0.74 TSHR (0.34) ALDH1A1LMNA
SCHEMBL7515278 0.69 HPGD (0.33) ALDH1A1HPGDSMN1; SMN2MAPTCA12
SCHEMBL11008658 0.67 ALDH1A1 (0.62) ALDH1A1LMNAHPGDSMN1; SMN2MAPT
SCHEMBL8053610 0.65 HPGD (0.36) ALDH1A1HPGDSMN1; SMN2MAPTCA12
SCHEMBL8930693 0.65 ALDH1A1 (0.38) ALDH1A1LMNAHPGDSMN1; SMN2MAPT
SCHEMBL522852 0.64 ALDH1A1 (0.54) ALDH1A1HPGDSMN1; SMN2MAPTCA12
SCHEMBL9397467 0.64 ALDH1A1 (0.58) ALDH1A1HPGDSMN1; SMN2MAPTCA12
SCHEMBL10444735 0.64 ALDH1A1 (0.58) ALDH1A1HPGDSMN1; SMN2MAPTCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5599522-A CONTRAST ENHANCING AGENTS NYCOMED IMAGING AS (NO) 1997-02-04 US disclosed
EP-0515458-B1 TRIARYLMETHYL RADICALS AND THE USE OF INERT CARBON FREE RADICALS IN MRI NYCOMED INNOVATION AB (SE) 1995-08-23 EP disclosed
EP-0515458-A1 TRIARYLMETHYL RADICALS AND THE USE OF INERT CARBON FREE RADICALS IN MRI. HAFSLUND NYCOMED INNOVATION (SE) 1992-12-02 EP disclosed
WO-1991012024-A1 TRIARYLMETHYL RADICALS AND THE USE OF INERT CARBON FREE RADICALS IN MRI HAFSLUND NYCOMED INNOVATION AB (SE) 1991-08-22 WO disclosed