Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7514564 | 0.81 | TSHR (0.45) | CYP3A4SMN1; SMN2TDP1CA12CA1 | |
| SCHEMBL8930717 | 0.77 | ALDH1A1 (0.39) | CYP3A4SMN1; SMN2TDP1NR1H2NR1H3 | |
| SCHEMBL12530071 | 0.77 | HPGD (0.45) | CYP3A4SMN1; SMN2TDP1NR1H2NR1H3 | |
| SCHEMBL7519849 | 0.75 | TSHR (0.50) | CYP3A4SMN1; SMN2HPGDTSHRALDH1A1 | |
| Methyl Alcohol SCHEMBL8930660 | 0.75 | LMNA (0.42) | SMN1; SMN2TDP1HPGDTSHRALDH1A1 | |
| SCHEMBL703438 | 0.73 | CA12 (0.53) | CYP3A4SMN1; SMN2CA12CA1CA2 | |
| SCHEMBL29781150 | 0.70 | GABRA1 (0.54) | SMN1; SMN2ALDH1A1KDM4EMAPTGLA | |
| SCHEMBL15746278 | 0.70 | TSHR (0.47) | SMN1; SMN2CA12CA1CA2CA7 | |
| SCHEMBL24140769 | 0.68 | CREBBP (0.41) | SMN1; SMN2TDP1CA12CA1CA2 | |
| SCHEMBL11008658 | 0.67 | ALDH1A1 (0.62) | CYP3A4SMN1; SMN2TDP1NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871896-B1 | A METHOD OF DETERMINING OXYGEN CONCENTRATION IN A SAMPLE | NYCOMED IMAGING AS (NO) | 2002-01-30 | — | — | EP | disclosed |
| US-6256527-B1 | Method for determining oxygen concentration | NYCOMED IMAGING AS (NO) | 2001-07-03 | — | — | US | disclosed |
| EP-0832054-B1 | HETEROCYCLIC METHYL FREE RADICALS AS IMAGE ENHANCING AGENTS | NYCOMED IMAGING AS (NO) | 2000-12-27 | — | — | EP | disclosed |
| US-6063360-A | USEFUL AS CONTRAST AGENT FOR OVERHAUSER MAGNETIC RESONACE IMAGING | NYCOMED IMAGING A/S (NO) | 2000-05-16 | — | — | US | disclosed |
| EP-0871896-A1 | A METHOD OF DETERMINING OXYGEN CONCENTRATION IN A SAMPLE | NYCOMED IMAGING AS (NO) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997009633-A1 | A METHOD OF DETERMINING OXYGEN CONCENTRATION IN A SAMPLE | NYCOMED IMAGING A/S (NO) | 1997-03-13 | — | — | WO | disclosed |
| WO-1996039367-A1 | HETEROCYCLIC METHYL FREE RADICALS AS IMAGE ENHANCING AGENTS | NYCOMED IMAGING A/S (NO) | 1996-12-12 | — | — | WO | disclosed |