SCHEMBL893104

SCHEMBL893104

N#Cc1ccc2c3cccc4cccc(c5cccc1c52)c43

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
KDM4E B2RXH2 1/20 0.50
GAA P10253 1/20 0.50
MAPT P10636 1/20 0.50
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CYP1A2 P05177 3/20 0.43
HPGD P15428 2/20 0.43
HSD17B10 Q99714 2/20 0.43
HTT P42858 1/20 0.43
THRB P10828 1/20 0.43
MCL1 Q07820 1/20 0.41
IMPDH2 P12268 2/20 0.40
IMPDH1 P20839 2/20 0.40
ERBB2 P04626 1/20 0.39
FYN P06241 1/20 0.39
MAOA P21397 1/20 0.39
ACHE P22303 1/20 0.39
AHR P35869 1/20 0.39
DYRK1A Q13627 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10620743 0.91 KDM4E (0.57) ALDH1A1KDM4EGAAMAPTCA1
SCHEMBL30427308 0.91 KDM4E (0.57) ALDH1A1KDM4EGAAMAPTCA1
SCHEMBL17502200 0.91 KDM4E (0.57) ALDH1A1KDM4EGAAMAPTCA1
SCHEMBL6263481 0.85 CA1 (0.42) ALDH1A1KDM4EGAAMAPTCA1
SCHEMBL29804460 0.85 ALDH1A1 (0.48) ALDH1A1KDM4EGAAMAPTCA1
SCHEMBL2350296 0.85 ALDH1A1 (0.48) ALDH1A1KDM4EGAAMAPTCA1
SCHEMBL12449285 0.84 ALDH1A1 (0.39) ALDH1A1KDM4EGAAMAPTCA1
SCHEMBL6239368 0.84 GAA (0.39) ALDH1A1KDM4EGAAMAPTCA1
SCHEMBL19154227 0.83 KDM4E (0.50) ALDH1A1KDM4EGAAMAPTCA1
SCHEMBL1062001 0.83 ALDH1A1 (0.41) ALDH1A1KDM4EGAAMAPTCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1090374-C Circuit protective device comprising PTC condcutive liquid crystal polymer composition EATON CORP (US) 2002-09-04 CN claimed
CN-1149746-A Circuit protective device comprising PTC condcutive liquid crystal polymer composition EATON CORP (US) 1997-05-14 CN claimed
WO-2016046779-A1 ZINC POLYAZAMACROCYCLIC COMPLEXES ENI S.P.A. (IT) 2016-03-31 WO disclosed
US-8664624-B2 Illumination delivery system for generating sustained secondary emission PERFORMANCE INDICATOR LLC (US) 2014-03-04 US disclosed
US-8519359-B2 Photolytically and environmentally stable multilayer structure for high efficiency electromagnetic energy conversion and sustained secondary emission PERFORMANCE INDICATOR, LLC (US) 2013-08-27 US disclosed
US-20130175456-A1 PHOTOLYTICALLY AND ENVIRONMENTALLY STABLE MULTILAYER STRUCTURE FOR HIGH EFFICIENCY ELECTROMAGNETIC ENERGY CONVERSION AND SUSTAINED SECONDARY EMISSION PERFORMANCE INDICATOR, LLC (US) 2013-07-11 US disclosed
US-20130088853-A1 ILLUMINATION DELIVERY SYSTEM FOR GENERATING SUSTAINED SECONDARY EMISSION PERFORMANCE INDICATOR, LLC (US) 2013-04-11 US disclosed
US-8415642-B2 Photolytically and environmentally stable multilayer structure for high efficiency electromagnetic energy conversion and sustained secondary emission PERFORMANCE INDICATOR, LLC (US) 2013-04-09 US disclosed
US-8232533-B2 Photolytically and environmentally stable multilayer structure for high efficiency electromagnetic energy conversion and sustained secondary emission PERFORMANCE INDICATOR, LLC (US) 2012-07-31 US disclosed
US-8178852-B2 Photolytically and environmentally stable multilayer structure for high efficiency electromagnetic energy conversion and sustained secondary emission PERFORMANCE INDICATOR, LLC (US) 2012-05-15 US disclosed
US-20120080615-A1 PHOTOLYTICALLY AND ENVIRONMENTALLY STABLE MULTILAYER STRUCTURE FOR HIGH EFFICIENCY ELECTROMAGENTIC ENERGY CONVERSION AND SUSTAINED SECONDARY EMISSION PERFORMANCE INDICATOR, LLC. (US) 2012-04-05 US disclosed
US-20120080614-A1 PHOTOLYTICALLY AND ENVIRONMENTALLY STABLE MULTILAYER STRUCTURE FOR HIGH EFFICIENCY ELECTROMAGENTIC ENERGY CONVERSION AND SUSTAINED SECONDARY EMISSION PERFORMANCE INDICATOR, LLC. (US) 2012-04-05 US disclosed
US-20120080613-A1 Photolytically and Environmentally Stable Multilayer Structure for High Efficiency Electromagnetic Energy Conversion and Sustained Secondary Emission PERFORMANCE INDICATOR, LLC. (US) 2012-04-05 US disclosed