SCHEMBL6239368

SCHEMBL6239368

N#Cc1ccc2c3cccc4cccc(c5cccc1c52)c43.NC(=O)NC(N)=O

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
KDM4E B2RXH2 2/20 0.39
ALDH1A1 P00352 2/20 0.39
MAPT P10636 1/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
MCL1 Q07820 1/20 0.38
SLC9A1 P19634 2/20 0.36
AR P10275 1/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
MTNR1A P48039 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
MAP1LC3B Q9GZQ8 1/20 0.33
HTT P42858 1/20 0.33
SLC22A12 Q96S37 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL893104 0.84 ALDH1A1 (0.50) GAAKDM4EALDH1A1MAPTCA1
SCHEMBL2332052 0.82 GAA (0.52) GAASMN1; SMN2KDM4EALDH1A1MAPT
SCHEMBL1128656 0.82 GAA (0.52) GAASMN1; SMN2KDM4EALDH1A1MAPT
SCHEMBL6263481 0.81 CA1 (0.42) GAAKDM4EALDH1A1MAPTCA1
Carbamic Acid SCHEMBL3399474 0.79 GAA (0.48) GAASMN1; SMN2KDM4EALDH1A1MAPT
SCHEMBL4690548 0.77 SLC9A1 (0.42) GAASMN1; SMN2KDM4EALDH1A1MAPT
SCHEMBL17502200 0.77 KDM4E (0.57) GAAKDM4EALDH1A1MAPTCA1
SCHEMBL30427308 0.77 KDM4E (0.57) GAAKDM4EALDH1A1MAPTCA1
SCHEMBL10620743 0.77 KDM4E (0.57) GAAKDM4EALDH1A1MAPTCA1
SCHEMBL4409157 0.76 ALDH1A1 (0.41) GAAKDM4EALDH1A1MAPTCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1542975-B1 9-CYANO-SUBSTITUTED PERYLENE-3,4-DICARBOXYLIC ACID MONOIMIDES BASF SE (DE) 2016-03-09 EP disclosed
EP-1542975-A2 9-CYANO-SUBSTITUTED PERYLENE-3,4-DICARBOXYLIC ACID MONOIMIDES BASF AKTIENGESELLSCHAFT (DE) 2005-06-22 EP disclosed
WO-2004029028-A2 9-CYANO-SUBSTITUTED PERYLENE-3,4-DICARBOXYLIC ACID MONOIMIDES AS DYESTUFFS BASF AKTIENGESELLSCHAFT (DE) 2004-04-08 WO disclosed