SCHEMBL8931070

SCHEMBL8931070

O=C1c2ccccc2C(=O)c2c1cccc2N(C(=O)c1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.60
MAPT P10636 5/20 0.60
L3MBTL1 Q9Y468 4/20 0.60
MAPK1 P28482 3/20 0.60
LMNA P02545 3/20 0.60
TDP1 Q9NUW8 2/20 0.60
NSD2 O96028 1/20 0.60
EGFR P00533 1/20 0.60
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53
PABPC1 P11940 2/20 0.53
KEAP1 Q14145 3/20 0.46
MAOA P21397 1/20 0.46
KDM4E B2RXH2 1/20 0.46
TTR P02766 3/20 0.43
ADORA2A P29274 1/20 0.43
RAB9A P51151 1/20 0.43
PTK2B Q14289 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
POLB P06746 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11785906 0.89 ALDH1A1 (0.59) ALDH1A1MAPTL3MBTL1MAPK1LMNA
SCHEMBL28995612 0.88 ALDH1A1 (0.58) ALDH1A1MAPTL3MBTL1MAPK1LMNA
SCHEMBL6142359 0.88 ADORA2A (0.54) ALDH1A1MAPTL3MBTL1MAPK1LMNA
SCHEMBL11841466 0.88 ADORA2A (0.54) ALDH1A1MAPTL3MBTL1MAPK1LMNA
SCHEMBL28004784 0.84 ALDH1A1 (0.53) ALDH1A1MAPTL3MBTL1MAPK1LMNA
SCHEMBL9802098 0.84 ALDH1A1 (0.53) ALDH1A1MAPTL3MBTL1MAPK1LMNA
SCHEMBL10697044 0.81 ALDH1A1 (0.71) ALDH1A1MAPTL3MBTL1MAPK1LMNA
SCHEMBL11573048 0.80 ALDH1A1 (0.48) ALDH1A1MAPTL3MBTL1MAPK1LMNA
SCHEMBL11847594 0.80 ALDH1A1 (0.41) ALDH1A1MAPTL3MBTL1MAPK1LMNA
SCHEMBL28658847 0.80 ALDH1A1 (0.48) ALDH1A1MAPTL3MBTL1MAPK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9268168-A None JP disclosed
JP-H09268168-A PRODUCTION OF 1-AMINO-5-BENZOYLAMINOANTHRAQUINONE MITSUI TOATSU CHEM INC 1997-10-14 JP disclosed
EP-0099071-B1 PROCESS FOR THE PREPARATION OF MONOBENZOYLATED 1,4-DIAMINOANTHRAQUINONES BAYER AG (DE) 1988-06-29 EP disclosed
EP-0099071-A2 Process for the preparation of monobenzoylated 1,4-diaminoanthraquinones BAYER AG (DE) 1984-01-25 EP disclosed
US-4324732-A IN PRESENCE OF TERITIARY ALIPHATIC AMINOALCOHOL AND/OR QUARTERNARY AMMONIUM COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1982-04-13 US disclosed
US-4231918-A THIOINDIGO OR DIOXAZINE PIGMENT AND DYE CIBA-GEIGY CORPORATION (US) 1980-11-04 US disclosed
US-4202815-A Concentrated powder or granular formulations dispersable in aqueous media ROHNER AG PRATTELN (CH) 1980-05-13 US disclosed
US-4179450-A Process for the preparation of 1-acylamino-5(8)-chloroanthraquinones BAYER AKTIENGESELLSCHAFT (DE) 1979-12-18 US disclosed
US-4165306-A Mass-dyeing of polyester with anthraquinone and benzanthrone dyes SANDOZ LTD. (CH) 1979-08-21 US disclosed
US-4141881-A PERYLENE-3,4,9,10-TETRACARBOXYLIC PIGMENT MIXTURE WITH DYE CIBA-GEIGY CORPORATION (US) 1979-02-27 US disclosed
US-4076736-A Preparation of aminoanthraquinones from nitroanthraquinones BAYER AKTIENGESELLSCHAFT (DT) 1978-02-28 US disclosed
US-3969302-A Process for the dyeing of colored shaped articles of high polymer, synthetic resins and preparations for such process CIBA-GEIGY AG (CH) 1976-07-13 US disclosed
US-3963762-A Process for producing 1,5-dinitroanthraquinone and 1,8-dinitroanthraquinone BAYER AKTIENGESELLSCHAFT (DT) 1976-06-15 US disclosed
US-3948828-A COLORING POLYESTERS OR POLYAMIDES CIBA-GEIGY CORPORATION (US) 1976-04-06 US disclosed